Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
Coch_1083KEGG: gfo:GFO_3236 hypothetical protein. (239 aa)    
Predicted Functional Partners:
Coch_1752
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
  
 0.770
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
   
 0.738
Coch_1082
PFAM: beta-lactamase; KEGG: gfo:GFO_3235 secreted beta-lactamase family protein.
  
    0.730
Coch_1383
Protein involved in gliding motility GldD; KEGG: fjo:Fjoh_1540 hypothetical protein.
  
     0.709
Coch_1633
Protein involved in gliding motility SprA; KEGG: fjo:Fjoh_1653 hypothetical protein.
  
 0.629
Coch_0756
PFAM: protein of unknown function DUF323; KEGG: gfo:GFO_2892 gliding motility protein GldJ.
  
     0.603
Coch_2029
SMART: Tetratricopeptide domain protein; KEGG: gfo:GFO_3274 hypothetical protein.
  
 
   0.592
Coch_1945
KEGG: gfo:GFO_1913 gliding motility protein GldG.
  
     0.588
Coch_1080
KEGG: bvu:BVU_2196 integral membrane protein.
     
 0.583
Coch_1081
KEGG: bfs:BF2712 hypothetical protein.
       0.580
Your Current Organism:
Capnocytophaga ochracea
NCBI taxonomy Id: 521097
Other names: C. ochracea DSM 7271, Capnocytophaga ochracea ATCC 27872, Capnocytophaga ochracea DSM 7271, Capnocytophaga ochracea str. DSM 7271, Capnocytophaga ochracea strain DSM 7271
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