Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Coch_1273Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: gfo:GFO_3230 delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. (328 aa)    
Predicted Functional Partners:
Coch_1454
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
 
 0.995
hemL
TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: aminotransferase class-III; KEGG: gfo:GFO_0240 glutamate-1-semialdehyde 2,1- aminomutase.
 
 
 0.992
hemA
glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
 
  
 0.854
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
 
 
 0.777
Coch_1477
PFAM: Uroporphyrinogen III synthase HEM4; KEGG: fps:FP0042 uroporphyrinogen-III synthase.
  
 
 0.731
Coch_0607
PFAM: Uroporphyrinogen III synthase HEM4; KEGG: gfo:GFO_0106 uroporphyrinogen-III synthase.
  
 
 0.701
Coch_2048
PFAM: Endonuclease/exonuclease/phosphatase; KEGG: fjo:Fjoh_1565 endonuclease/exonuclease/phosphatase.
      0.614
Coch_1272
KEGG: gfo:GFO_2570 hypothetical protein.
       0.592
Coch_1499
TIGRFAM: malonyl CoA-acyl carrier protein transacylase; PFAM: Acyl transferase; KEGG: fps:FP0408 malonyl CoA-acyl carrier protein transacylase.
 
    
 0.561
ribB
3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.
  
  
 0.549
Your Current Organism:
Capnocytophaga ochracea
NCBI taxonomy Id: 521097
Other names: C. ochracea DSM 7271, Capnocytophaga ochracea ATCC 27872, Capnocytophaga ochracea DSM 7271, Capnocytophaga ochracea str. DSM 7271, Capnocytophaga ochracea strain DSM 7271
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