Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Coch_1685Cystathionine gamma-synthase; PFAM: Cys/Met metabolism pyridoxal-phosphate- dependent protein; KEGG: cac:CAC0390 cystathionine gamma-synthase. (378 aa)    
Predicted Functional Partners:
Coch_1829
PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: gfo:GFO_1794 cysteine synthase/cystathionine beta-synthase.
 
 0.983
Coch_1822
TIGRFAM: cysteine synthase A; cysteine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: fjo:Fjoh_4653 cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family.
 
 0.980
Coch_0411
KEGG: fjo:Fjoh_1494 aspartate kinase; TIGRFAM: aspartate kinase; PFAM: homoserine dehydrogenase; amino acid-binding ACT domain protein; homoserine dehydrogenase NAD-binding; aspartate/glutamate/uridylate kinase.
  
 
 0.975
Coch_0087
PFAM: aminotransferase class I and II; KEGG: bfs:BF0911 putative aminotransferase.
 
 
 0.965
Coch_1115
PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; flavodoxin/nitric oxide synthase; PepSY- associated TM helix domain protein; KEGG: fjo:Fjoh_4069 flavodoxin/nitric oxide synthase.
  
 
 0.936
Coch_1623
PFAM: aminotransferase class I and II; KEGG: fps:FP1696 aspartate aminotransferase.
  
 
 0.923
Coch_2047
PFAM: aminotransferase class I and II; KEGG: fps:FP0412 aspartate transaminase AspC1.
  
 
 0.923
metE
5-methyltetrahydropteroyltriglutamate/homocystei neS-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family.
  
 
 0.922
Coch_1601
KEGG: gfo:GFO_0499 branched-chain-amino-acid aminotransferase; TIGRFAM: branched-chain amino acid aminotransferase; PFAM: aminotransferase class IV.
   
 0.918
Coch_0409
PFAM: alpha/beta hydrolase fold; KEGG: fps:FP0256 homoserine O-acetyltransferase; Belongs to the AB hydrolase superfamily. MetX family.
 
  
 0.905
Your Current Organism:
Capnocytophaga ochracea
NCBI taxonomy Id: 521097
Other names: C. ochracea DSM 7271, Capnocytophaga ochracea ATCC 27872, Capnocytophaga ochracea DSM 7271, Capnocytophaga ochracea str. DSM 7271, Capnocytophaga ochracea strain DSM 7271
Server load: low (8%) [HD]