STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Coch_1822TIGRFAM: cysteine synthase A; cysteine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: fjo:Fjoh_4653 cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (302 aa)    
Predicted Functional Partners:
Coch_1821
Serine O-acetyltransferase; PFAM: transferase hexapeptide repeat containing protein; KEGG: chu:CHU_0685 serine O-acetyltransferase.
 
 0.996
Coch_1685
Cystathionine gamma-synthase; PFAM: Cys/Met metabolism pyridoxal-phosphate- dependent protein; KEGG: cac:CAC0390 cystathionine gamma-synthase.
 
 0.980
Coch_1115
PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; flavodoxin/nitric oxide synthase; PepSY- associated TM helix domain protein; KEGG: fjo:Fjoh_4069 flavodoxin/nitric oxide synthase.
  
 
 0.966
Coch_0087
PFAM: aminotransferase class I and II; KEGG: bfs:BF0911 putative aminotransferase.
    
 0.915
serC
Phosphoserine transaminase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
  
 
 0.915
Coch_1623
PFAM: aminotransferase class I and II; KEGG: fps:FP1696 aspartate aminotransferase.
   
 0.909
Coch_2047
PFAM: aminotransferase class I and II; KEGG: fps:FP0412 aspartate transaminase AspC1.
   
 0.909
Coch_1216
Quorum-sensing autoinducer 2 (AI-2), LuxS; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family.
  
 
 0.853
Coch_1829
PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: gfo:GFO_1794 cysteine synthase/cystathionine beta-synthase.
  
  
 
0.834
metE
5-methyltetrahydropteroyltriglutamate/homocystei neS-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family.
   
 
 0.826
Your Current Organism:
Capnocytophaga ochracea
NCBI taxonomy Id: 521097
Other names: C. ochracea DSM 7271, Capnocytophaga ochracea ATCC 27872, Capnocytophaga ochracea DSM 7271, Capnocytophaga ochracea str. DSM 7271, Capnocytophaga ochracea strain DSM 7271
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.