Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Coch_2125PFAM: protein of unknown function DUF214; KEGG: gfo:GFO_2398 lipoprotein releasing system transmembrane protein. (412 aa)    
Predicted Functional Partners:
lolD
ABC transporter related; Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
  
 0.941
Coch_0778
PFAM: protein of unknown function DUF214; KEGG: fps:FP0239 ABC transporter permease.
  
  
 
0.929
Coch_1357
TIGRFAM: outer membrane protein assembly complex, YaeT protein; PFAM: surface antigen (D15); surface antigen variable number repeat protein; KEGG: fps:FP2096 outer membrane protein precursor.
 
   
 0.727
macB
ABC transporter related; Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP- binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
  
 
 0.721
Coch_0386
PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: pdi:BDI_3354 putative ABC transporter ATP- binding protein.
  
 
 0.721
Coch_2124
PFAM: conserved hypothetical protein; KEGG: gfo:GFO_2399 secreted protein containing DUF1343.
       0.652
Coch_1810
TIGRFAM: signal peptidase I; PFAM: peptidase S24 and S26 domain protein; KEGG: gfo:GFO_0802 signal peptidase I; Belongs to the peptidase S26 family.
  
  
 0.619
Coch_0509
KEGG: fjo:Fjoh_0663 hypothetical protein.
 
     0.594
Coch_1461
KEGG: fjo:Fjoh_2111 hypothetical protein.
 
 
 
 0.561
Coch_0220
Two component transcriptional regulator, AraC family; PFAM: response regulator receiver; periplasmic binding protein/LacI transcriptional regulator; ATP- binding region ATPase domain protein; histidine kinase A domain protein; helix-turn-helix- domain containing protein AraC type; SMART: response regulator receiver; helix-turn- helix- domain containing protein AraC type; histidine kinase A domain protein; ATP-binding region ATPase domain protein; KEGG: bvu:BVU_1666 putative two-component system sensor histidine kinase/response regulator, hybrid.
  
 
 0.538
Your Current Organism:
Capnocytophaga ochracea
NCBI taxonomy Id: 521097
Other names: C. ochracea DSM 7271, Capnocytophaga ochracea ATCC 27872, Capnocytophaga ochracea DSM 7271, Capnocytophaga ochracea str. DSM 7271, Capnocytophaga ochracea strain DSM 7271
Server load: low (10%) [HD]