Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Coch_2146PFAM: Rhomboid family protein; KEGG: fps:FP1148 rhomboid family protein. (258 aa)    
Predicted Functional Partners:
Coch_1836
PFAM: Rhomboid family protein; KEGG: fjo:Fjoh_4502 rhomboid family protein.
  
     0.703
mutL
DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
  
    0.646
Coch_2147
PFAM: protein of unknown function DUF1260; Protein of unknown function DUF695; KEGG: fnu:FN0296 putative cytoplasmic protein.
       0.644
Coch_2153
PFAM: protein of unknown function UPF0118; KEGG: fps:FP1620 putative transporting permease.
 
    0.582
aroC
Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
  
  
 0.573
Coch_2148
KEGG: fps:FP0664 hypothetical protein.
       0.533
Coch_2150
KEGG: tme:Tmel_0308 DNA adenine methylase; TIGRFAM: DNA adenine methylase; PFAM: D12 class N6 adenine-specific DNA methyltransferase.
       0.520
Coch_2151
KEGG: emi:Emin_0685 hypothetical protein.
       0.520
Coch_2152
PFAM: DNA methylase N-4/N-6 domain protein; KEGG: cha:CHAB381_1229 DNA methylase; Belongs to the N(4)/N(6)-methyltransferase family.
       0.520
Coch_1800
TIGRFAM: 5-formyltetrahydrofolate cyclo-ligase; PFAM: 5-formyltetrahydrofolate cyclo-ligase; KEGG: gfo:GFO_3177 5-formyltetrahydrofolate cyclo- ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.
  
  
 0.513
Your Current Organism:
Capnocytophaga ochracea
NCBI taxonomy Id: 521097
Other names: C. ochracea DSM 7271, Capnocytophaga ochracea ATCC 27872, Capnocytophaga ochracea DSM 7271, Capnocytophaga ochracea str. DSM 7271, Capnocytophaga ochracea strain DSM 7271
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