STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Aaci_1652Hypothetical protein; KEGG: vap:Vapar_0529 methyltransferase type 11. (307 aa)    
Predicted Functional Partners:
dinG
Exonuclease RNase T and DNA polymerase III; 3'-5' exonuclease.
       0.806
ku
Ku protein; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family.
       0.699
birA
biotin/acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
     
 0.613
Aaci_1654
tRNA cytidylyltransferase; PFAM: Polynucleotide adenylyltransferase region; KEGG: afw:Anae109_2353 tRNA cytidylyltransferase.
       0.566
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
  
  
 0.566
Aaci_1655
PFAM: glycosyl transferase group 1; KEGG: mxa:MXAN_6195 glycosyl transferase, group 1 family protein.
       0.539
dapB
Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family.
       0.499
Aaci_1657
PFAM: MazG nucleotide pyrophosphohydrolase; KEGG: sml:Smlt3663 hypothetical protein.
       0.490
Aaci_0673
Signal transduction histidine kinase with CheB and CheR activity; KEGG: scl:sce4190 hypothetical protein; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; CheB methylesterase; MCP methyltransferase CheR-type; PAS fold domain protein; PAS fold-4 domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; SMART: MCP methyltransferase CheR-type; PAC repeat- containing protein; histidine kinase A domain protein; PAS domain containing protein; ATP-binding region ATPase domain protein.
     
 0.442
Your Current Organism:
Alicyclobacillus acidocaldarius DSM 446
NCBI taxonomy Id: 521098
Other names: A. acidocaldarius subsp. acidocaldarius DSM 446, Alicyclobacillus acidocaldarius subsp. acidocaldarius ATCC 27009, Alicyclobacillus acidocaldarius subsp. acidocaldarius DSM 446, Alicyclobacillus acidocaldarius subsp. acidocaldarius IFO 15652, Alicyclobacillus acidocaldarius subsp. acidocaldarius JCM 5260, Alicyclobacillus acidocaldarius subsp. acidocaldarius NBRC 15652, Alicyclobacillus acidocaldarius subsp. acidocaldarius NCIB 11725, Alicyclobacillus acidocaldarius subsp. acidocaldarius str. DSM 446, Alicyclobacillus acidocaldarius subsp. acidocaldarius strain DSM 446
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