STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
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[Homology]
Score
Aaci_1697Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat. (492 aa)    
Predicted Functional Partners:
Aaci_2752
TIGRFAM: SpoIID/LytB domain protein; KEGG: gsu:GSU2621 stage II sporulation-related protein.
  
  
 0.847
Aaci_2750
TIGRFAM: sporulation transcriptional regulator SpoIIID; KEGG: atc:AGR_pAT_567 ribose operon repressor.
  
  
 0.843
Aaci_1790
TIGRFAM: stage III sporulation protein AD; PFAM: Sporulation stage III protein AD.
  
    0.840
Aaci_1793
TIGRFAM: stage III sporulation protein AA; SMART: AAA ATPase; KEGG: Os07g0187400; hypothetical protein.
  
  
 0.814
Aaci_2778
TIGRFAM: stage II sporulation protein R; PFAM: Sporulation stage II protein R.
  
   
 0.809
spoIIAB
Anti-sigma regulatory factor, serine/threonine protein kinase; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
  
  
 0.806
Aaci_1291
RNA polymerase, sigma 28 subunit, SigG; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
  
 0.804
gpr
Spore protease; Initiates the rapid degradation of small, acid-soluble proteins during spore germination; Belongs to the peptidase A25 family.
  
   
 0.804
Aaci_1767
Sporulation transcriptional activator Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
  
   
 0.794
Aaci_0183
TIGRFAM: stage V sporulation protein T; transcriptional regulator, AbrB family; PFAM: SpoVT/AbrB domain protein.
  
  
 0.788
Your Current Organism:
Alicyclobacillus acidocaldarius DSM 446
NCBI taxonomy Id: 521098
Other names: A. acidocaldarius subsp. acidocaldarius DSM 446, Alicyclobacillus acidocaldarius subsp. acidocaldarius ATCC 27009, Alicyclobacillus acidocaldarius subsp. acidocaldarius DSM 446, Alicyclobacillus acidocaldarius subsp. acidocaldarius IFO 15652, Alicyclobacillus acidocaldarius subsp. acidocaldarius JCM 5260, Alicyclobacillus acidocaldarius subsp. acidocaldarius NBRC 15652, Alicyclobacillus acidocaldarius subsp. acidocaldarius NCIB 11725, Alicyclobacillus acidocaldarius subsp. acidocaldarius str. DSM 446, Alicyclobacillus acidocaldarius subsp. acidocaldarius strain DSM 446
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