node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Aaci_2452 | Aaci_2856 | Aaci_2452 | Aaci_2856 | PFAM: AMP-dependent synthetase and ligase; KEGG: noc:Noc_2380 AMP-dependent synthetase and ligase. | 8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. | 0.516 |
Aaci_2452 | birA | Aaci_2452 | Aaci_1653 | PFAM: AMP-dependent synthetase and ligase; KEGG: noc:Noc_2380 AMP-dependent synthetase and ligase. | biotin/acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | 0.434 |
Aaci_2668 | Aaci_2856 | Aaci_2668 | Aaci_2856 | PFAM: aminotransferase class-III; KEGG: dvm:DvMF_0516 aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. | 0.566 |
Aaci_2668 | bioB | Aaci_2668 | Aaci_2854 | PFAM: aminotransferase class-III; KEGG: dvm:DvMF_0516 aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.793 |
Aaci_2668 | bioD | Aaci_2668 | Aaci_2855 | PFAM: aminotransferase class-III; KEGG: dvm:DvMF_0516 aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Dethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | 0.797 |
Aaci_2668 | birA | Aaci_2668 | Aaci_1653 | PFAM: aminotransferase class-III; KEGG: dvm:DvMF_0516 aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | biotin/acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | 0.456 |
Aaci_2856 | Aaci_2452 | Aaci_2856 | Aaci_2452 | 8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. | PFAM: AMP-dependent synthetase and ligase; KEGG: noc:Noc_2380 AMP-dependent synthetase and ligase. | 0.516 |
Aaci_2856 | Aaci_2668 | Aaci_2856 | Aaci_2668 | 8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. | PFAM: aminotransferase class-III; KEGG: dvm:DvMF_0516 aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.566 |
Aaci_2856 | Aaci_2858 | Aaci_2856 | Aaci_2858 | 8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. | PFAM: monooxygenase FAD-binding; KEGG: mxa:MXAN_3398 FAD-dependent oxidoreductase. | 0.579 |
Aaci_2856 | Aaci_2859 | Aaci_2856 | Aaci_2859 | 8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. | PFAM: conserved hypothetical protein; KEGG: eic:NT01EI_2385 hypothetical protein. | 0.616 |
Aaci_2856 | Aaci_2860 | Aaci_2856 | Aaci_2860 | 8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. | PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: rlg:Rleg_5124 polar amino acid ABC transporter, inner membrane subunit; Belongs to the ABC transporter superfamily. | 0.491 |
Aaci_2856 | bioA | Aaci_2856 | Aaci_2857 | 8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. | Adenosylmethionine-8-amino-7-oxononanoateaminotr ansferase; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily. | 0.993 |
Aaci_2856 | bioB | Aaci_2856 | Aaci_2854 | 8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.953 |
Aaci_2856 | bioD | Aaci_2856 | Aaci_2855 | 8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. | Dethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | 0.986 |
Aaci_2856 | birA | Aaci_2856 | Aaci_1653 | 8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. | biotin/acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | 0.508 |
Aaci_2856 | gcvT | Aaci_2856 | Aaci_1800 | 8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. | Glycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine. | 0.491 |
Aaci_2858 | Aaci_2856 | Aaci_2858 | Aaci_2856 | PFAM: monooxygenase FAD-binding; KEGG: mxa:MXAN_3398 FAD-dependent oxidoreductase. | 8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. | 0.579 |
Aaci_2858 | Aaci_2859 | Aaci_2858 | Aaci_2859 | PFAM: monooxygenase FAD-binding; KEGG: mxa:MXAN_3398 FAD-dependent oxidoreductase. | PFAM: conserved hypothetical protein; KEGG: eic:NT01EI_2385 hypothetical protein. | 0.773 |
Aaci_2858 | Aaci_2860 | Aaci_2858 | Aaci_2860 | PFAM: monooxygenase FAD-binding; KEGG: mxa:MXAN_3398 FAD-dependent oxidoreductase. | PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: rlg:Rleg_5124 polar amino acid ABC transporter, inner membrane subunit; Belongs to the ABC transporter superfamily. | 0.773 |
Aaci_2858 | bioA | Aaci_2858 | Aaci_2857 | PFAM: monooxygenase FAD-binding; KEGG: mxa:MXAN_3398 FAD-dependent oxidoreductase. | Adenosylmethionine-8-amino-7-oxononanoateaminotr ansferase; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily. | 0.487 |