STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Athe_0149TIGRFAM: PTS system, fructose subfamily, IIC subunit; PTS system, fructose-specific, IIB subunnit; PFAM: phosphotransferase system PTS fructose-specific IIB subunit; phosphotransferase system EIIC; KEGG: csc:Csac_2439 PTS system, fructose subfamily, IIC subunit. (454 aa)    
Predicted Functional Partners:
Athe_0147
TIGRFAM: 1-phosphofructokinase; PFAM: PfkB domain protein; KEGG: csc:Csac_2441 ribokinase-like domain-containing protein; Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
 
 
 0.999
Athe_0148
Putative PTS IIA-like nitrogen-regulatory protein PtsN; TIGRFAM: PTS system, fructose subfamily, IIA subunit; PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; KEGG: csc:Csac_2440 putative PTS IIA-like nitrogen-regulatory protein PtsN.
  
 0.998
Athe_0151
Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
 
  
 0.996
Athe_0150
TIGRFAM: phosphocarrier, HPr family; PFAM: phosphoryl transfer system HPr; KEGG: csc:Csac_2438 phosphotransferase system, phosphocarrier protein HPr.
  
 
 0.993
Athe_0323
TIGRFAM: phosphocarrier, HPr family; PFAM: phosphoryl transfer system HPr; KEGG: csc:Csac_1163 phosphotransferase system, phosphocarrier protein HPr.
  
 
 0.985
Athe_1281
KEGG: csc:Csac_1846 hypothetical protein.
  
 
 0.985
Athe_0621
KEGG: csc:Csac_1189 fructose-1,6-bisphosphate aldolase, class II; TIGRFAM: fructose-1,6-bisphosphate aldolase, class II; ketose-bisphosphate aldolase; PFAM: ketose-bisphosphate aldolase class-II.
  
 
 0.952
Athe_1995
KEGG: csc:Csac_0349 ketose-bisphosphate aldolase; TIGRFAM: ketose-bisphosphate aldolase; PFAM: ketose-bisphosphate aldolase class-II.
  
 
 0.952
Athe_2390
KEGG: csc:Csac_0349 ketose-bisphosphate aldolase; TIGRFAM: ketose-bisphosphate aldolase; PFAM: ketose-bisphosphate aldolase class-II.
  
 
 0.952
xylA
KEGG: tpd:Teth39_2060 xylose isomerase; TIGRFAM: xylose isomerase; PFAM: Xylose isomerase domain protein TIM barrel; Belongs to the xylose isomerase family.
     
 0.937
Your Current Organism:
Caldicellulosiruptor bescii
NCBI taxonomy Id: 521460
Other names: Anaerocellum thermophilum DSM 6725, C. bescii DSM 6725, Caldicellulosiruptor becscii str. DSM 6725, Caldicellulosiruptor bescii DSM 6725, Caldicellulosiruptor bescii strain DSM 6725
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.