STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Athe_0210KEGG: csc:Csac_0110 dihydropteroate synthase; TIGRFAM: dihydropteroate synthase; PFAM: dihydropteroate synthase DHPS. (376 aa)    
Predicted Functional Partners:
Athe_0212
KEGG: csc:Csac_0112 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 78-dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK.
  
 0.998
Athe_1490
TIGRFAM: FolC bifunctional protein; PFAM: Mur ligase middle domain protein; cytoplasmic peptidoglycan synthetase domain protein; KEGG: csc:Csac_2037 FolC bifunctional protein; Belongs to the folylpolyglutamate synthase family.
 
 0.996
Athe_2216
PFAM: aminotransferase class IV; KEGG: tex:Teth514_0616 aminotransferase, class IV.
 
 
 0.939
Athe_0500
PFAM: beta-lactamase domain protein; KEGG: csc:Csac_1140 beta-lactamase domain-containing protein.
     
 0.906
birA
biotin/acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
     
 0.875
Athe_0208
PFAM: protein of unknown function DUF1284; KEGG: csc:Csac_0108 hypothetical protein.
       0.723
Athe_0211
KEGG: csc:Csac_0111 hypothetical protein.
       0.695
Athe_0213
PFAM: short-chain dehydrogenase/reductase SDR; KEGG: csc:Csac_0113 short-chain dehydrogenase/reductase SDR.
     
 0.695
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
  
 0.605
Athe_0214
PFAM: protein of unknown function DUF820; KEGG: csc:Csac_0114 hypothetical protein.
       0.604
Your Current Organism:
Caldicellulosiruptor bescii
NCBI taxonomy Id: 521460
Other names: Anaerocellum thermophilum DSM 6725, C. bescii DSM 6725, Caldicellulosiruptor becscii str. DSM 6725, Caldicellulosiruptor bescii DSM 6725, Caldicellulosiruptor bescii strain DSM 6725
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.