STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Athe_0243PFAM: TrkA-N domain protein; KEGG: csc:Csac_0151 TrkA domain-containing protein. (206 aa)    
Predicted Functional Partners:
Athe_0240
PFAM: cation transporter; KEGG: csc:Csac_0149 cation transporter.
 
 
 0.986
Athe_0242
PFAM: TrkA-N domain protein; TrkA-C domain protein; KEGG: csc:Csac_0150 TrkA domain-containing protein.
 
    
0.847
Athe_0241
Hypothetical protein.
       0.714
Athe_0239
KEGG: csc:Csac_0148 hypothetical protein.
       0.643
Athe_1042
Fmu (Sun) domain protein; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.
  
   0.596
queA
S-adenosylmethionine/tRNA-ribosyltransferase- isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
  
    0.540
Athe_1199
TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; KEGG: csc:Csac_1652 uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family.
  
    0.538
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
  
 0.529
Athe_0244
TIGRFAM: SpoIID/LytB domain protein; PFAM: Stage II sporulation D domain protein; KEGG: csc:Csac_0152 SpoIID/LytB domain-containing protein.
       0.517
pheT
KEGG: csc:Csac_1849 phenylalanyl-tRNA synthetase, beta subunit; TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit.
 
     0.451
Your Current Organism:
Caldicellulosiruptor bescii
NCBI taxonomy Id: 521460
Other names: Anaerocellum thermophilum DSM 6725, C. bescii DSM 6725, Caldicellulosiruptor becscii str. DSM 6725, Caldicellulosiruptor bescii DSM 6725, Caldicellulosiruptor bescii strain DSM 6725
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