STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Athe_0450PFAM: response regulator receiver; SMART: response regulator receiver; KEGG: sak:SAK_0189 DNA-binding response regulator. (253 aa)    
Predicted Functional Partners:
Athe_1455
Histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; KEGG: csc:Csac_2002 integral membrane sensor signal transduction histidine kinase.
 
 
 0.805
Athe_1750
Histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; KEGG: csc:Csac_2293 integral membrane sensor signal transduction histidine kinase.
 
 
 0.795
Athe_0451
KEGG: ana:all3465 unknown protein.
  
    0.789
Athe_0452
PFAM: glycosyl transferase family 2; KEGG: aoe:Clos_0614 glycosyl transferase family protein.
  
  
 0.784
Athe_0279
Histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; KEGG: mta:Moth_1477 periplasmic sensor signal transduction histidine kinase.
 
 
 0.762
Athe_2589
PFAM: histidine kinase A domain protein; histidine kinase HAMP region domain protein; ATP-binding region ATPase domain protein; SMART: histidine kinase A domain protein; histidine kinase HAMP region domain protein; ATP-binding region ATPase domain protein; KEGG: csc:Csac_0419 integral membrane sensor signal transduction histidine kinase.
 
 
 0.736
Athe_0081
KEGG: csc:Csac_2558 multi-sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein.
 
 
 0.721
Athe_1486
Histidine kinase; KEGG: csc:Csac_2033 integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein.
 
 
 0.705
Athe_1456
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: csc:Csac_2003 two component transcriptional regulator.
  
     0.693
Athe_2740
KEGG: csc:Csac_0020 diguanylate cyclase/phosphodiesterase with PAS/PAC and GAF sensor(s); TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: EAL domain protein; PAS fold-3 domain protein; GGDEF domain containing protein; extracellular solute-binding protein family 3; PAS fold-4 domain protein; PAS fold domain protein; SMART: EAL domain protein; GGDEF domain containing protein; PAC repeat-containing protein; extracellular solute-binding protein family 3; PAS domain containing protein.
  
 
 0.665
Your Current Organism:
Caldicellulosiruptor bescii
NCBI taxonomy Id: 521460
Other names: Anaerocellum thermophilum DSM 6725, C. bescii DSM 6725, Caldicellulosiruptor becscii str. DSM 6725, Caldicellulosiruptor bescii DSM 6725, Caldicellulosiruptor bescii strain DSM 6725
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.