STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Athe_0465PFAM: aldo/keto reductase; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: csc:Csac_1115 aldo/keto reductase. (340 aa)    
Predicted Functional Partners:
Athe_0466
PFAM: ABC transporter related; ABC transporter transmembrane region; SMART: AAA ATPase; KEGG: csc:Csac_1116 ABC transporter related.
       0.782
Athe_0467
CRISPR-associated protein Cas6; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
       0.723
Athe_1893
PFAM: protein of unknown function DUF1121; KEGG: csc:Csac_1051 hypothetical protein.
   
   0.466
Athe_2382
PFAM: protein of unknown function DUF1121; KEGG: cac:CAC0356 hypothetical protein.
   
   0.466
Athe_0468
PFAM: glycoside hydrolase clan GH-D; KEGG: csc:Csac_1118 glycoside hydrolase, clan GH-D.
       0.456
Athe_0464
Non-specific serine/threonine protein kinase; KEGG: cth:Cthe_2451 SNF2-related protein; PFAM: SNF2-related protein; SNF2 helicase associated domain protein; helicase domain protein; SMART: DEAD-like helicases; helicase domain protein.
       0.453
Athe_2135
PFAM: protein of unknown function DUF362; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: csc:Csac_1294 hypothetical protein.
 
    0.438
Your Current Organism:
Caldicellulosiruptor bescii
NCBI taxonomy Id: 521460
Other names: Anaerocellum thermophilum DSM 6725, C. bescii DSM 6725, Caldicellulosiruptor becscii str. DSM 6725, Caldicellulosiruptor bescii DSM 6725, Caldicellulosiruptor bescii strain DSM 6725
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