STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Athe_0573PFAM: cyclase family protein; KEGG: csc:Csac_0804 cyclase family protein. (209 aa)    
Predicted Functional Partners:
Athe_1062
PFAM: malic protein NAD-binding; malic protein domain protein; KEGG: csc:Csac_2059 malate dehydrogenase.
   
 
  0.801
pckG
Phosphoenolpyruvate carboxykinase (GTP); Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
     
  0.800
Athe_0510
TIGRFAM: hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit; PFAM: Fe-S type hydro-lyase tartrate/fumarate beta region; KEGG: csc:Csac_0738 tartrate/fumarate subfamily Fe-S type hydro-lyase beta subunit.
     
  0.800
Athe_1319
PFAM: Conserved carboxylase region; pyruvate carboxyltransferase; KEGG: csc:Csac_1883 hypothetical protein.
     
  0.800
Athe_2746
KEGG: csc:Csac_2759 tartrate/fumarate subfamily Fe-S type hydro-lyase alpha subunit; TIGRFAM: hydro-lyase, Fe-S type, tartrate/fumarate subfamily, alpha subunit; PFAM: Fe-S type hydro-lyase tartrate/fumarate alpha region.
     
  0.800
proS
prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves dea [...]
       0.529
Athe_0569
PFAM: ANTAR domain protein; KEGG: csc:Csac_0800 response regulator receiver/ANTAR domain-containing protein.
       0.452
Athe_0570
PFAM: peptidase C26; KEGG: csc:Csac_0801 peptidase C26.
       0.452
Athe_0571
PFAM: MscS Mechanosensitive ion channel; KEGG: csc:Csac_0802 MscS mechanosensitive ion channel.
       0.452
Athe_0574
PFAM: chemotaxis sensory transducer; SMART: chemotaxis sensory transducer; KEGG: csc:Csac_0811 methyl-accepting chemotaxis sensory transducer.
       0.405
Your Current Organism:
Caldicellulosiruptor bescii
NCBI taxonomy Id: 521460
Other names: Anaerocellum thermophilum DSM 6725, C. bescii DSM 6725, Caldicellulosiruptor becscii str. DSM 6725, Caldicellulosiruptor bescii DSM 6725, Caldicellulosiruptor bescii strain DSM 6725
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