STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Athe_0589TIGRFAM: cation diffusion facilitator family transporter; PFAM: cation efflux protein; KEGG: csc:Csac_0826 cation diffusion facilitator family transporter; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. (285 aa)    
Predicted Functional Partners:
ldh
L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family.
  
    0.741
Athe_2280
TIGRFAM: heavy metal translocating P-type ATPase; copper-translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC; copper ion binding protein; cadmium-translocating P-type ATPase; PFAM: E1-E2 ATPase-associated domain protein; Heavy metal transport/detoxification protein; Haloacid dehalogenase domain protein hydrolase; KEGG: csc:Csac_0225 heavy metal translocating P-type ATPase.
  
 
 0.597
Athe_2337
TIGRFAM: flagellar basal-body rod protein FlgG; PFAM: protein of unknown function DUF1078 domain protein; flagellar basal body rod protein; KEGG: csc:Csac_0595 hypothetical protein.
    
 
 0.587
crcB
CrcB protein; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family.
     
 0.457
crcB-2
CrcB protein; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family.
     
 0.457
Athe_2338
PFAM: flagellar basal body rod protein; protein of unknown function DUF1078 domain protein; KEGG: csc:Csac_0594 flagellar basal body rod protein.
    
 
 0.442
Athe_0588
KEGG: csc:Csac_0825 hypothetical protein.
       0.438
Athe_2740
KEGG: csc:Csac_0020 diguanylate cyclase/phosphodiesterase with PAS/PAC and GAF sensor(s); TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: EAL domain protein; PAS fold-3 domain protein; GGDEF domain containing protein; extracellular solute-binding protein family 3; PAS fold-4 domain protein; PAS fold domain protein; SMART: EAL domain protein; GGDEF domain containing protein; PAC repeat-containing protein; extracellular solute-binding protein family 3; PAS domain containing protein.
  
  
 0.434
nadE
NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
  
   0.414
Athe_0587
KEGG: csc:Csac_0824 hypothetical protein.
       0.410
Your Current Organism:
Caldicellulosiruptor bescii
NCBI taxonomy Id: 521460
Other names: Anaerocellum thermophilum DSM 6725, C. bescii DSM 6725, Caldicellulosiruptor becscii str. DSM 6725, Caldicellulosiruptor bescii DSM 6725, Caldicellulosiruptor bescii strain DSM 6725
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