STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
Athe_0609KEGG: csc:Csac_0689 pullulanase, type I; TIGRFAM: pullulanase, type I; PFAM: pullanase-associated protein; glycoside hydrolase starch-binding; glycoside hydrolase family 13 domain protein; alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain; Belongs to the glycosyl hydrolase 13 family. (1136 aa)    
Predicted Functional Partners:
Athe_0556
TIGRFAM: glucose-1-phosphate adenylyltransferase, GlgD subunit; KEGG: csc:Csac_0782 glucose-1-phosphate adenylyltransferase, GlgD subunit.
 
 
 0.975
glgC
Glucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
 
 
 0.972
glgB
1,4-alpha-glucan branching enzyme; Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position; Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
 
 
0.972
Athe_2593
PFAM: alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain; KEGG: csc:Csac_0408 alpha amylase, catalytic region; Belongs to the glycosyl hydrolase 13 family.
 
 0.961
Athe_0554
Glycogen/starch/alpha-glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.
 
 
 0.947
Athe_2579
PFAM: alpha amylase catalytic region; glycoside hydrolase family 13 domain protein Ig domain protein region domain protein; SMART: alpha amylase catalytic sub domain; KEGG: csc:Csac_0426 alpha amylase, catalytic region.
 
0.941
Athe_2576
TIGRFAM: alpha-glucan phosphorylase; PFAM: glycosyl transferase family 35; KEGG: csc:Csac_0429 alpha-glucan phosphorylase.
  
 
 0.934
Athe_1151
TIGRFAM: UTP-glucose-1-phosphate uridylyltransferase; PFAM: Nucleotidyl transferase; KEGG: csc:Csac_1600 UTP-glucose-1-phosphate uridylyltransferase GalU.
     
 0.907
Athe_0228
PFAM: glycoside hydrolase 15-related; KEGG: csc:Csac_0130 glycoside hydrolase 15-related.
    
 0.905
Athe_0448
KEGG: csc:Csac_0671 pullulanase, type I; TIGRFAM: pullulanase, type I; PFAM: glycoside hydrolase family 13 domain protein; alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain; Belongs to the glycosyl hydrolase 13 family.
  
  
 
0.905
Your Current Organism:
Caldicellulosiruptor bescii
NCBI taxonomy Id: 521460
Other names: Anaerocellum thermophilum DSM 6725, C. bescii DSM 6725, Caldicellulosiruptor becscii str. DSM 6725, Caldicellulosiruptor bescii DSM 6725, Caldicellulosiruptor bescii strain DSM 6725
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