STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Athe_0822PFAM: thiamineS protein; KEGG: csc:Csac_0970 hypothetical protein. (76 aa)    
Predicted Functional Partners:
Athe_0823
PFAM: UBA/THIF-type NAD/FAD binding protein; KEGG: csc:Csac_0971 UBA/ThiF-type NAD/FAD binding protein.
  
 
 0.947
Athe_0369
Thiazole biosynthesis family protein; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
  
 
 0.914
Athe_0821
KEGG: csc:Csac_0969 aldehyde ferredoxin oxidoreductase; PFAM: Aldehyde ferredoxin oxidoreductase; aldehyde ferredoxin oxidoreductase; SMART: Aldehyde ferredoxin oxidoreductase.
       0.794
Athe_0820
PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: csc:Csac_0968 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein.
       0.782
Athe_1186
PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; KEGG: csc:Csac_1635 UBA/ThiF-type NAD/FAD binding protein.
  
 
 0.775
Athe_1187
PFAM: Mov34/MPN/PAD-1 family protein; SMART: Mov34/MPN/PAD-1 family protein; KEGG: csc:Csac_1636 Mov34/MPN/PAD-1 family protein.
  
 
 0.734
thiE
Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
  
  
 0.549
Athe_0373
TIGRFAM: thiamine biosynthesis protein ThiC; PFAM: thiamine biosynthesis protein ThiC; KEGG: csc:Csac_0255 thiamine biosynthesis protein ThiC.
  
  
 0.543
Athe_0195
PFAM: PP-loop domain protein; KEGG: csc:Csac_0104 PP-loop domain-containing protein; Belongs to the TtcA family.
  
   0.540
tilS
tRNA(Ile)-lysidine synthetase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family.
  
   0.540
Your Current Organism:
Caldicellulosiruptor bescii
NCBI taxonomy Id: 521460
Other names: Anaerocellum thermophilum DSM 6725, C. bescii DSM 6725, Caldicellulosiruptor becscii str. DSM 6725, Caldicellulosiruptor bescii DSM 6725, Caldicellulosiruptor bescii strain DSM 6725
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