STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Athe_0832PFAM: GCN5-related N-acetyltransferase; KEGG: csc:Csac_0980 GCN5-related N-acetyltransferase. (128 aa)    
Predicted Functional Partners:
Athe_0833
MCP methyltransferase, CheR-type; KEGG: csc:Csac_0981 protein-glutamate O-methyltransferase; PFAM: MCP methyltransferase CheR-type; SMART: MCP methyltransferase CheR-type.
       0.702
Athe_0834
KEGG: csc:Csac_0982 hypothetical protein.
       0.702
Athe_0835
PFAM: glycosyl transferase family 4; KEGG: csc:Csac_0983 glycosyl transferase family protein.
       0.702
Athe_0831
TIGRFAM: molybdenum cofactor synthesis domain protein; PFAM: molybdopterin binding domain; KEGG: csc:Csac_0979 molybdenum cofactor synthesis domain-containing protein.
       0.537
Athe_0840
PFAM: GCN5-related N-acetyltransferase; KEGG: csc:Csac_0988 GCN5-related N-acetyltransferase.
  
  
 0.470
Athe_0836
KEGG: csc:Csac_0984 hypothetical protein.
       0.469
rph
Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
     
 0.449
Athe_0838
Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
       0.433
Athe_0839
TIGRFAM: phosphodiesterase, MJ0936 family; PFAM: metallophosphoesterase; KEGG: csc:Csac_0987 phosphodiesterase.
       0.433
Your Current Organism:
Caldicellulosiruptor bescii
NCBI taxonomy Id: 521460
Other names: Anaerocellum thermophilum DSM 6725, C. bescii DSM 6725, Caldicellulosiruptor becscii str. DSM 6725, Caldicellulosiruptor bescii DSM 6725, Caldicellulosiruptor bescii strain DSM 6725
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