STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Athe_0848KEGG: csc:Csac_2695 uroporphyrinogen-III decarboxylase-like protein; Belongs to the uroporphyrinogen decarboxylase family. (361 aa)    
Predicted Functional Partners:
Athe_1199
TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; KEGG: csc:Csac_1652 uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family.
  
 
 0.969
Athe_1554
Oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family.
  
 
 0.916
Athe_1198
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
  
 
 0.704
Athe_2260
KEGG: csc:Csac_0697 hypothetical protein.
  
     0.702
Athe_1885
PFAM: response regulator receiver; SMART: response regulator receiver; KEGG: csc:Csac_1059 response regulator receiver protein.
 
   
 0.672
Athe_0181
PFAM: extracellular solute-binding protein family 1; KEGG: csc:Csac_2412 extracellular solute-binding protein.
  
     0.671
Athe_2570
PFAM: MORN variant repeat protein; KEGG: csc:Csac_0283 hypothetical protein.
  
     0.671
Athe_2566
PFAM: MORN variant repeat protein; KEGG: csc:Csac_0283 hypothetical protein.
  
     0.670
Athe_2572
KEGG: csc:Csac_0278 hypothetical protein.
  
     0.667
Athe_2120
PFAM: Ig domain protein group 2 domain protein; Thrombospondin type 3 repeat; von Willebrand factor type A; SMART: von Willebrand factor type A; Parallel beta-helix repeat; Ig domain protein group 2 domain protein; KEGG: csc:Csac_1310 Ig domain-containing protein.
 
   
 0.657
Your Current Organism:
Caldicellulosiruptor bescii
NCBI taxonomy Id: 521460
Other names: Anaerocellum thermophilum DSM 6725, C. bescii DSM 6725, Caldicellulosiruptor becscii str. DSM 6725, Caldicellulosiruptor bescii DSM 6725, Caldicellulosiruptor bescii strain DSM 6725
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