STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Athe_0853Two component transcriptional regulator, AraC family; PFAM: response regulator receiver; helix-turn-helix- domain containing protein AraC type; SMART: response regulator receiver; helix-turn-helix- domain containing protein AraC type; KEGG: csc:Csac_2690 response regulator receiver protein. (509 aa)    
Predicted Functional Partners:
Athe_0852
Putative sensor with HAMP domain; PFAM: histidine kinase internal region; ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; SMART: histidine kinase HAMP region domain protein; KEGG: csc:Csac_2691 integral membrane sensor signal transduction histidine kinase.
 
 
 0.961
Athe_2056
Putative sensor with HAMP domain; PFAM: histidine kinase internal region; ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; SMART: histidine kinase HAMP region domain protein; ATP-binding region ATPase domain protein; KEGG: csc:Csac_1355 integral membrane sensor signal transduction histidine kinase.
 
 
 0.878
Athe_2551
Signal transduction histidine kinase, LytS; PFAM: histidine kinase internal region; ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; SMART: histidine kinase HAMP region domain protein; KEGG: csc:Csac_0300 histidine kinase internal region.
 
 0.873
Athe_0599
Putative sensor with HAMP domain; PFAM: histidine kinase internal region; ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; SMART: histidine kinase HAMP region domain protein; KEGG: csc:Csac_0683 histidine kinase internal region.
 
 0.862
Athe_0103
Signal transduction histidine kinase, LytS; PFAM: histidine kinase internal region; ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; SMART: histidine kinase HAMP region domain protein; ATP-binding region ATPase domain protein; KEGG: csc:Csac_2508 signal transduction histidine kinase, LytS.
 
 0.831
Athe_2372
PFAM: histidine kinase internal region; ATP-binding region ATPase domain protein; KEGG: cpy:Cphy_0617 signal transduction histidine kinase, LytS.
 
 
 0.807
Athe_1455
Histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; KEGG: csc:Csac_2002 integral membrane sensor signal transduction histidine kinase.
  
 
   0.738
Athe_2161
TIGRFAM: flagellar motor switch protein FliM; PFAM: flagellar motor switch protein FliM; surface presentation of antigens (SPOA) protein; KEGG: csc:Csac_1269 flagellar motor switch protein FliM.
  
 
 0.712
Athe_1750
Histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; KEGG: csc:Csac_2293 integral membrane sensor signal transduction histidine kinase.
  
 
   0.708
Athe_0849
PFAM: extracellular solute-binding protein family 1; KEGG: csc:Csac_2694 extracellular solute-binding protein.
 
   
 0.680
Your Current Organism:
Caldicellulosiruptor bescii
NCBI taxonomy Id: 521460
Other names: Anaerocellum thermophilum DSM 6725, C. bescii DSM 6725, Caldicellulosiruptor becscii str. DSM 6725, Caldicellulosiruptor bescii DSM 6725, Caldicellulosiruptor bescii strain DSM 6725
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.