STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Athe_0855PFAM: Mannitol dehydrogenase domain; Mannitol dehydrogenase rossman domain; KEGG: csc:Csac_2688 mannitol dehydrogenase domain-containing protein. (539 aa)    
Predicted Functional Partners:
uxuA
Mannonate dehydratase; Catalyzes the dehydration of D-mannonate.
 
 
 0.996
uxaC
PFAM: Glucuronate isomerase; KEGG: csc:Csac_1949 glucuronate isomerase.
 
 
 0.987
Athe_0854
Alpha-glucuronidase; PFAM: Glycosyl hydrolase 67 middle domain protein; glycosyl hydrolase 67 C-teriminal domain protein; glycoside hydrolase family 67; KEGG: csc:Csac_2689 alpha-glucuronidase; Belongs to the glycosyl hydrolase 67 family.
 
   
 0.750
Athe_0857
PFAM: glycoside hydrolase family 2 sugar binding; glycoside hydrolase family 2 immunoglobulin domain protein beta-sandwich; glycoside hydrolase family 2 TIM barrel; KEGG: csc:Csac_2686 glycoside hydrolase family protein; Belongs to the glycosyl hydrolase 2 family.
     
 0.564
Athe_0853
Two component transcriptional regulator, AraC family; PFAM: response regulator receiver; helix-turn-helix- domain containing protein AraC type; SMART: response regulator receiver; helix-turn-helix- domain containing protein AraC type; KEGG: csc:Csac_2690 response regulator receiver protein.
  
    0.519
Athe_0852
Putative sensor with HAMP domain; PFAM: histidine kinase internal region; ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; SMART: histidine kinase HAMP region domain protein; KEGG: csc:Csac_2691 integral membrane sensor signal transduction histidine kinase.
       0.465
Athe_2385
PFAM: PfkB domain protein; KEGG: csc:Csac_2720 ribokinase-like domain-containing protein.
 
   
 0.430
Athe_0149
TIGRFAM: PTS system, fructose subfamily, IIC subunit; PTS system, fructose-specific, IIB subunnit; PFAM: phosphotransferase system PTS fructose-specific IIB subunit; phosphotransferase system EIIC; KEGG: csc:Csac_2439 PTS system, fructose subfamily, IIC subunit.
  
  
 0.418
Athe_2386
TIGRFAM: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; PFAM: KDPG and KHG aldolase; KEGG: csc:Csac_0354 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase.
 
  
 0.407
pgk
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
     
 0.401
Your Current Organism:
Caldicellulosiruptor bescii
NCBI taxonomy Id: 521460
Other names: Anaerocellum thermophilum DSM 6725, C. bescii DSM 6725, Caldicellulosiruptor becscii str. DSM 6725, Caldicellulosiruptor bescii DSM 6725, Caldicellulosiruptor bescii strain DSM 6725
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.