STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Athe_1069PFAM: protein of unknown function DUF1385; KEGG: csc:Csac_1521 hypothetical protein. (313 aa)    
Predicted Functional Partners:
prmC
Modification methylase, HemK family; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
      0.974
prfA
Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
  
    0.807
Athe_1315
TIGRFAM: agmatinase; PFAM: Arginase/agmatinase/formiminoglutamase; KEGG: csc:Csac_1880 putative agmatinase; Belongs to the arginase family.
   
    0.758
rpmE
Ribosomal protein L31; Binds the 23S rRNA.
       0.703
Athe_1074
PFAM: zinc/iron permease; KEGG: csc:Csac_1526 zinc/iron permease.
       0.558
Athe_1075
Sua5/YciO/YrdC/YwlC family protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.
       0.558
Athe_1076
PFAM: Protein-tyrosine phosphatase, low molecular weight; SMART: Protein-tyrosine phosphatase, low molecular weight; KEGG: csc:Csac_1528 protein tyrosine phosphatase.
       0.558
Athe_1072
PFAM: MotA/TolQ/ExbB proton channel; KEGG: csc:Csac_1524 MotA/TolQ/ExbB proton channel.
       0.532
Athe_1073
PFAM: OmpA/MotB domain protein; KEGG: csc:Csac_1525 OmpA/MotB domain-containing protein.
       0.532
Athe_0604
KEGG: csc:Csac_0687 hypothetical protein.
   
    0.502
Your Current Organism:
Caldicellulosiruptor bescii
NCBI taxonomy Id: 521460
Other names: Anaerocellum thermophilum DSM 6725, C. bescii DSM 6725, Caldicellulosiruptor becscii str. DSM 6725, Caldicellulosiruptor bescii DSM 6725, Caldicellulosiruptor bescii strain DSM 6725
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