STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Athe_1291PFAM: ATP-binding region ATPase domain protein; KEGG: csc:Csac_1856 putative anti-sigma regulatory factor, serine/threonine protein kinase. (139 aa)    
Predicted Functional Partners:
Athe_1290
KEGG: csc:Csac_1855 hypothetical protein.
   
 0.988
Athe_1292
PFAM: Fe-S cluster domain protein; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: csc:Csac_1857 Fe-S cluster domain-containing protein.
   
 0.960
Athe_1293
KEGG: csc:Csac_1858 hypothetical protein.
 
   
 0.947
Athe_1294
PFAM: PHP domain protein; SMART: phosphoesterase PHP domain protein; KEGG: csc:Csac_1859 phosphotransferase domain-containing protein.
 
   
 0.943
Athe_1296
Histidine kinase; PFAM: ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; KEGG: csc:Csac_1861 histidine kinase.
 
  
 0.899
Athe_1297
KEGG: csc:Csac_1862 hypothetical protein.
 
   
 0.892
Athe_0435
Anti-sigma-factor antagonist; TIGRFAM: anti-anti-sigma factor; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; KEGG: csc:Csac_0458 anti-sigma-factor antagonist.
  
 
 0.884
Athe_1682
Anti-sigma-factor antagonist; TIGRFAM: anti-anti-sigma factor; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; KEGG: csc:Csac_1657 anti-sigma-factor antagonist.
  
 
 0.860
Athe_2740
KEGG: csc:Csac_0020 diguanylate cyclase/phosphodiesterase with PAS/PAC and GAF sensor(s); TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: EAL domain protein; PAS fold-3 domain protein; GGDEF domain containing protein; extracellular solute-binding protein family 3; PAS fold-4 domain protein; PAS fold domain protein; SMART: EAL domain protein; GGDEF domain containing protein; PAC repeat-containing protein; extracellular solute-binding protein family 3; PAS domain containing protein.
  
 
 0.750
Athe_2749
KEGG: csc:Csac_2762 putative PAS/PAC sensor protein; TIGRFAM: PAS sensor protein; PFAM: Stage II sporulation E family protein; PAS fold-4 domain protein; SMART: protein phosphatase 2C domain protein.
  
 
 0.734
Your Current Organism:
Caldicellulosiruptor bescii
NCBI taxonomy Id: 521460
Other names: Anaerocellum thermophilum DSM 6725, C. bescii DSM 6725, Caldicellulosiruptor becscii str. DSM 6725, Caldicellulosiruptor bescii DSM 6725, Caldicellulosiruptor bescii strain DSM 6725
Server load: low (32%) [HD]