STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Athe_1324Chorismate mutase; Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis. (124 aa)    
Predicted Functional Partners:
aroC
Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
  
 
 0.952
cmk
KEGG: csc:Csac_1889 cytidylate kinase; TIGRFAM: cytidylate kinase; PFAM: cytidylate kinase region.
      0.940
Athe_0844
PFAM: Prephenate dehydrogenase; KEGG: csc:Csac_2699 prephenate dehydrogenase.
  
 
  0.937
pheA
PFAM: prephenate dehydratase; amino acid-binding ACT domain protein; KEGG: csc:Csac_1462 prephenate dehydratase.
    
 0.918
Athe_1695
TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: glutamine amidotransferase class-I; KEGG: csc:Csac_2235 glutamine amidotransferase of anthranilate synthase.
    
  0.904
Athe_1696
PFAM: Chorismate binding-like; KEGG: csc:Csac_2236 anthranilate synthase.
    
 0.904
Athe_1958
PFAM: amino acid-binding ACT domain protein; KEGG: csc:Csac_0995 hypothetical protein; Belongs to the UPF0735 family.
     
  0.900
Athe_1326
PFAM: phospholipid/glycerol acyltransferase; SMART: phospholipid/glycerol acyltransferase; KEGG: csc:Csac_1890 phospholipid/glycerol acyltransferase.
     
 0.838
Athe_2217
Anthranilate synthase; PFAM: Chorismate binding-like; Anthranilate synthase component I domain protein; KEGG: tex:Teth514_0615 para-aminobenzoate synthase, subunit I.
    
 0.809
Athe_2218
TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: glutamine amidotransferase class-I; KEGG: csc:Csac_0728 glutamine amidotransferase of anthranilate synthase.
    
  0.809
Your Current Organism:
Caldicellulosiruptor bescii
NCBI taxonomy Id: 521460
Other names: Anaerocellum thermophilum DSM 6725, C. bescii DSM 6725, Caldicellulosiruptor becscii str. DSM 6725, Caldicellulosiruptor bescii DSM 6725, Caldicellulosiruptor bescii strain DSM 6725
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