node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Athe_1374 | carA | Athe_1374 | Athe_1540 | TIGRFAM: uracil-xanthine permease; PFAM: Xanthine/uracil/vitamin C permease; KEGG: csc:Csac_1930 uracil-xanthine permease. | TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: Carbamoyl-phosphate synthase small chain; glutamine amidotransferase class-I; KEGG: csc:Csac_2227 carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. | 0.856 |
Athe_1374 | carB | Athe_1374 | Athe_1378 | TIGRFAM: uracil-xanthine permease; PFAM: Xanthine/uracil/vitamin C permease; KEGG: csc:Csac_1930 uracil-xanthine permease. | TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; protein of unknown function DUF201; phosphoribosylglycinamide synthetase; MGS domain protein; Carbamoyl-phosphate synthetase large chain oligomerisation; Carbamoyl-phosphate synthetase large chain domain protein; KEGG: csc:Csac_1934 carbamoyl phosphate synthase large subunit; Belongs to the CarB family. | 0.874 |
Athe_1374 | pyrB | Athe_1374 | Athe_1375 | TIGRFAM: uracil-xanthine permease; PFAM: Xanthine/uracil/vitamin C permease; KEGG: csc:Csac_1930 uracil-xanthine permease. | KEGG: csc:Csac_1931 aspartate carbamoyltransferase; TIGRFAM: aspartate carbamoyltransferase; PFAM: aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.995 |
Athe_1374 | pyrC | Athe_1374 | Athe_1376 | TIGRFAM: uracil-xanthine permease; PFAM: Xanthine/uracil/vitamin C permease; KEGG: csc:Csac_1930 uracil-xanthine permease. | Dihydroorotase, multifunctional complex type; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | 0.988 |
Athe_1374 | pyrD | Athe_1374 | Athe_1380 | TIGRFAM: uracil-xanthine permease; PFAM: Xanthine/uracil/vitamin C permease; KEGG: csc:Csac_1930 uracil-xanthine permease. | Dihydroorotate dehydrogenase family protein; Catalyzes the conversion of dihydroorotate to orotate with NAD(+) as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily. | 0.931 |
Athe_1374 | pyrE | Athe_1374 | Athe_1382 | TIGRFAM: uracil-xanthine permease; PFAM: Xanthine/uracil/vitamin C permease; KEGG: csc:Csac_1930 uracil-xanthine permease. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.962 |
Athe_1374 | pyrF | Athe_1374 | Athe_1377 | TIGRFAM: uracil-xanthine permease; PFAM: Xanthine/uracil/vitamin C permease; KEGG: csc:Csac_1930 uracil-xanthine permease. | TIGRFAM: orotidine 5'-phosphate decarboxylase; PFAM: Orotidine 5'-phosphate decarboxylase; KEGG: csc:Csac_1933 orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. Type 2 subfamily. | 0.965 |
Athe_1374 | pyrR | Athe_1374 | Athe_1373 | TIGRFAM: uracil-xanthine permease; PFAM: Xanthine/uracil/vitamin C permease; KEGG: csc:Csac_1930 uracil-xanthine permease. | Uracil phosphoribosyltransferase; Regulates transcriptional attenuation of the pyrimidine nucleotide (pyr) operon by binding in a uridine-dependent manner to specific sites on pyr mRNA. This disrupts an antiterminator hairpin in the RNA and favors formation of a downstream transcription terminator, leading to a reduced expression of downstream genes. Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily. | 0.991 |
Athe_1374 | upp | Athe_1374 | Athe_0633 | TIGRFAM: uracil-xanthine permease; PFAM: Xanthine/uracil/vitamin C permease; KEGG: csc:Csac_1930 uracil-xanthine permease. | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. | 0.616 |
carA | Athe_1374 | Athe_1540 | Athe_1374 | TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: Carbamoyl-phosphate synthase small chain; glutamine amidotransferase class-I; KEGG: csc:Csac_2227 carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. | TIGRFAM: uracil-xanthine permease; PFAM: Xanthine/uracil/vitamin C permease; KEGG: csc:Csac_1930 uracil-xanthine permease. | 0.856 |
carA | carB | Athe_1540 | Athe_1378 | TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: Carbamoyl-phosphate synthase small chain; glutamine amidotransferase class-I; KEGG: csc:Csac_2227 carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. | TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; protein of unknown function DUF201; phosphoribosylglycinamide synthetase; MGS domain protein; Carbamoyl-phosphate synthetase large chain oligomerisation; Carbamoyl-phosphate synthetase large chain domain protein; KEGG: csc:Csac_1934 carbamoyl phosphate synthase large subunit; Belongs to the CarB family. | 0.999 |
carA | pyrB | Athe_1540 | Athe_1375 | TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: Carbamoyl-phosphate synthase small chain; glutamine amidotransferase class-I; KEGG: csc:Csac_2227 carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. | KEGG: csc:Csac_1931 aspartate carbamoyltransferase; TIGRFAM: aspartate carbamoyltransferase; PFAM: aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.999 |
carA | pyrC | Athe_1540 | Athe_1376 | TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: Carbamoyl-phosphate synthase small chain; glutamine amidotransferase class-I; KEGG: csc:Csac_2227 carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. | Dihydroorotase, multifunctional complex type; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | 0.997 |
carA | pyrD | Athe_1540 | Athe_1380 | TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: Carbamoyl-phosphate synthase small chain; glutamine amidotransferase class-I; KEGG: csc:Csac_2227 carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. | Dihydroorotate dehydrogenase family protein; Catalyzes the conversion of dihydroorotate to orotate with NAD(+) as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily. | 0.911 |
carA | pyrE | Athe_1540 | Athe_1382 | TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: Carbamoyl-phosphate synthase small chain; glutamine amidotransferase class-I; KEGG: csc:Csac_2227 carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.963 |
carA | pyrF | Athe_1540 | Athe_1377 | TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: Carbamoyl-phosphate synthase small chain; glutamine amidotransferase class-I; KEGG: csc:Csac_2227 carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. | TIGRFAM: orotidine 5'-phosphate decarboxylase; PFAM: Orotidine 5'-phosphate decarboxylase; KEGG: csc:Csac_1933 orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. Type 2 subfamily. | 0.972 |
carA | pyrR | Athe_1540 | Athe_1373 | TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: Carbamoyl-phosphate synthase small chain; glutamine amidotransferase class-I; KEGG: csc:Csac_2227 carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. | Uracil phosphoribosyltransferase; Regulates transcriptional attenuation of the pyrimidine nucleotide (pyr) operon by binding in a uridine-dependent manner to specific sites on pyr mRNA. This disrupts an antiterminator hairpin in the RNA and favors formation of a downstream transcription terminator, leading to a reduced expression of downstream genes. Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily. | 0.829 |
carA | upp | Athe_1540 | Athe_0633 | TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: Carbamoyl-phosphate synthase small chain; glutamine amidotransferase class-I; KEGG: csc:Csac_2227 carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. | 0.522 |
carB | Athe_1374 | Athe_1378 | Athe_1374 | TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; protein of unknown function DUF201; phosphoribosylglycinamide synthetase; MGS domain protein; Carbamoyl-phosphate synthetase large chain oligomerisation; Carbamoyl-phosphate synthetase large chain domain protein; KEGG: csc:Csac_1934 carbamoyl phosphate synthase large subunit; Belongs to the CarB family. | TIGRFAM: uracil-xanthine permease; PFAM: Xanthine/uracil/vitamin C permease; KEGG: csc:Csac_1930 uracil-xanthine permease. | 0.874 |
carB | carA | Athe_1378 | Athe_1540 | TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; protein of unknown function DUF201; phosphoribosylglycinamide synthetase; MGS domain protein; Carbamoyl-phosphate synthetase large chain oligomerisation; Carbamoyl-phosphate synthetase large chain domain protein; KEGG: csc:Csac_1934 carbamoyl phosphate synthase large subunit; Belongs to the CarB family. | TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: Carbamoyl-phosphate synthase small chain; glutamine amidotransferase class-I; KEGG: csc:Csac_2227 carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. | 0.999 |