STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
panDAspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. (128 aa)    
Predicted Functional Partners:
panC
Pantoate/beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.
 
 
 0.999
panB
3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family.
 
  
 0.993
Athe_1982
KEGG: csc:Csac_2711 6-phosphogluconate dehydrogenase, NAD-binding.
 
     0.905
Athe_1213
L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate.
    
 0.839
Athe_0474
PFAM: fumarate lyase; KEGG: csc:Csac_1124 aspartate ammonia-lyase.
     
 0.820
Athe_1128
PFAM: aminotransferase class I and II; KEGG: csc:Csac_1578 aminotransferase, class I and II.
    
 0.813
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
    
  0.809
argG
KEGG: csc:Csac_1814 argininosuccinate synthase; TIGRFAM: argininosuccinate synthase; PFAM: argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily.
     
  0.800
pyrB
KEGG: csc:Csac_1931 aspartate carbamoyltransferase; TIGRFAM: aspartate carbamoyltransferase; PFAM: aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
     
  0.800
Athe_1539
KEGG: csc:Csac_2226 asparagine synthase (glutamine-hydrolyzing); TIGRFAM: asparagine synthase (glutamine-hydrolyzing); PFAM: asparagine synthase; glutamine amidotransferase class-II.
     
  0.800
Your Current Organism:
Caldicellulosiruptor bescii
NCBI taxonomy Id: 521460
Other names: Anaerocellum thermophilum DSM 6725, C. bescii DSM 6725, Caldicellulosiruptor becscii str. DSM 6725, Caldicellulosiruptor bescii DSM 6725, Caldicellulosiruptor bescii strain DSM 6725
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