STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Athe_1989Superfamily I DNA and RNA helicase and helicase subunits-like protein; KEGG: bfs:BF2029 putative ATP-binding protein. (605 aa)    
Predicted Functional Partners:
Athe_1823
PFAM: Fibronectin-binding A domain protein; protein of unknown function DUF814; KEGG: csc:Csac_2365 fibronectin-binding A domain-containing protein.
  
    0.781
nnrD
Carbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow t [...]
  
    0.457
Athe_1988
TIGRFAM: transcriptional regulator, AbrB family; PFAM: SpoVT/AbrB domain protein; KEGG: csc:Csac_2496 hypothetical protein.
  
    0.435
Athe_2478
PFAM: N-6 DNA methylase; putative RNA methylase; KEGG: rbe:RBE_0858 type I restriction-modification system methyltransferase subunit.
  
  
 0.429
Athe_2514
KEGG: tth:TTC1428 hypothetical protein.
  
  
 0.429
Athe_1987
PFAM: PilT protein domain protein; KEGG: csc:Csac_2495 hypothetical protein.
       0.424
Athe_1990
Hypothetical protein.
       0.409
Athe_1991
Hypothetical protein; KEGG: bfs:BF2029 putative ATP-binding protein.
       0.409
Your Current Organism:
Caldicellulosiruptor bescii
NCBI taxonomy Id: 521460
Other names: Anaerocellum thermophilum DSM 6725, C. bescii DSM 6725, Caldicellulosiruptor becscii str. DSM 6725, Caldicellulosiruptor bescii DSM 6725, Caldicellulosiruptor bescii strain DSM 6725
Server load: medium (46%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.