STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Athe_2106PFAM: protein of unknown function DUF362; KEGG: csc:Csac_1323 hypothetical protein. (360 aa)    
Predicted Functional Partners:
dnaX
DNA polymerase III, subunits gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
       0.755
rnr
Ribonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
       0.709
Athe_2109
TIGRFAM: metal dependent phophohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; KEGG: csc:Csac_1320 metal dependent phosphohydrolase.
 
     0.701
Athe_2389
PFAM: Xylose isomerase domain protein TIM barrel; KEGG: csc:Csac_0350 xylose isomerase domain-containing protein.
  
     0.579
Athe_2110
TIGRFAM: transposase; transposase, IS605 OrfB family; KEGG: csc:Csac_0831 transposase, putative.
       0.473
Athe_1643
PFAM: DNA polymerase beta domain protein region; KEGG: csc:Csac_1709 DNA polymerase beta subunit.
  
     0.439
Athe_1650
KEGG: csc:Csac_1702 hypothetical protein.
  
     0.435
hpf
Sigma 54 modulation protein/ribosomal protein S30EA; Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.
       0.416
Athe_2084
PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; HI0933 family protein; KEGG: tle:Tlet_1879 succinate dehydrogenase.
  
     0.407
Athe_2369
KEGG: csc:Csac_0363 hypothetical protein.
  
     0.403
Your Current Organism:
Caldicellulosiruptor bescii
NCBI taxonomy Id: 521460
Other names: Anaerocellum thermophilum DSM 6725, C. bescii DSM 6725, Caldicellulosiruptor becscii str. DSM 6725, Caldicellulosiruptor bescii DSM 6725, Caldicellulosiruptor bescii strain DSM 6725
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