STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Athe_2139Transcriptional regulator, AraC family; PFAM: helix-turn-helix- domain containing protein AraC type; Cupin 2 conserved barrel domain protein; SMART: helix-turn-helix- domain containing protein AraC type; KEGG: csc:Csac_1290 helix-turn-helix domain-containing protein. (282 aa)    
Predicted Functional Partners:
Athe_2642
Transcriptional regulator, AraC family; PFAM: helix-turn-helix- domain containing protein AraC type; SMART: helix-turn-helix- domain containing protein AraC type; KEGG: csc:Csac_0497 helix-turn-helix domain-containing protein.
 
 
0.820
Athe_2033
Transcriptional regulator, AraC family; PFAM: helix-turn-helix- domain containing protein AraC type; SMART: helix-turn-helix- domain containing protein AraC type; KEGG: cpy:Cphy_2187 AraC family transcriptional regulator.
  
   0.798
sigA
RNA polymerase, sigma 70 subunit, RpoD subfamily; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
    
 
 0.747
Athe_2423
TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70 region 4 type 2; sigma-70 region 2 domain protein; KEGG: gur:Gura_2617 RpoD family RNA polymerase sigma factor.
    
 
 0.747
Athe_2140
KEGG: csc:Csac_1289 hypothetical protein.
       0.736
Athe_2337
TIGRFAM: flagellar basal-body rod protein FlgG; PFAM: protein of unknown function DUF1078 domain protein; flagellar basal body rod protein; KEGG: csc:Csac_0595 hypothetical protein.
   
   0.733
Athe_2338
PFAM: flagellar basal body rod protein; protein of unknown function DUF1078 domain protein; KEGG: csc:Csac_0594 flagellar basal body rod protein.
   
   0.733
Athe_2141
KEGG: csc:Csac_1288 hypothetical protein.
       0.676
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.631
Athe_2434
Transcriptional regulator, XRE family; PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; KEGG: drm:Dred_0888 XRE family transcriptional regulator.
  
 
 0.622
Your Current Organism:
Caldicellulosiruptor bescii
NCBI taxonomy Id: 521460
Other names: Anaerocellum thermophilum DSM 6725, C. bescii DSM 6725, Caldicellulosiruptor becscii str. DSM 6725, Caldicellulosiruptor bescii DSM 6725, Caldicellulosiruptor bescii strain DSM 6725
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.