STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Plim_0263TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: E1-E2 ATPase-associated domain protein; cation transporting ATPase domain protein; Haloacid dehalogenase domain protein hydrolase; KEGG: ppd:Ppro_3226 ATPase, P-type (transporting), HAD superfamily, subfamily IC. (917 aa)    
Predicted Functional Partners:
Plim_3056
FAD-binding domain protein.
    
 0.845
Plim_3267
Protein of unknown function DUF692; KEGG: Srrm2; serine/arginine repetitive matrix 2.
   
    0.774
Plim_3170
Hypothetical protein.
  
 
 0.745
Plim_0757
PFAM: sodium/hydrogen exchanger; TrkA-N domain protein; TrkA-C domain protein; KEGG: dol:Dole_0855 sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.
  
 
 0.710
atpE
H+transporting two-sector ATPase C subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
   
 0.625
Plim_0262
PFAM: regulatory protein MarR; SMART: regulatory protein MarR; KEGG: aba:Acid345_2954 transcriptional regulator, MarR family.
  
    0.586
Plim_2369
PFAM: AMP-dependent synthetase and ligase; phospholipid/glycerol acyltransferase; major facilitator superfamily MFS_1; SMART: phospholipid/glycerol acyltransferase; KEGG: aba:Acid345_4052 2-acyl-glycerophospho- ethanolamine acyltransferase.
  
 0.575
Plim_0933
KEGG: acr:Acry_3027 heavy metal translocating P- type ATPase; TIGRFAM: heavy metal translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: E1-E2 ATPase-associated domain protein; Haloacid dehalogenase domain protein hydrolase.
 
 
 0.489
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
   
 
 0.475
Plim_2188
PFAM: Tetratricopeptide TPR_2 repeat protein; TPR repeat-containing protein; SMART: BRCT domain protein; Tetratricopeptide domain protein; KEGG: scl:sce3861 MerR family transcriptional regulator.
  
  
 0.474
Your Current Organism:
Planctopirus limnophila
NCBI taxonomy Id: 521674
Other names: P. limnophila DSM 3776, Planctomyces limnophilus ATCC 43296, Planctomyces limnophilus DSM 3776, Planctomyces limnophilus str. DSM 3776, Planctomyces limnophilus strain DSM 3776, Planctopirus limnophila DSM 3776, Planctopirus limnophilus DSM 3776
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.