STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
Plim_0663PFAM: chaperone DnaJ domain protein; heat shock protein DnaJ domain protein; SMART: heat shock protein DnaJ domain protein; KEGG: dvu:DVU1876 DnaJ protein, putative. (310 aa)    
Predicted Functional Partners:
grpE
GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...]
 
 
 0.950
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
 
  0.931
Plim_3027
Heat shock protein 70.
 
  0.906
Plim_3585
Heat shock protein 70.
 
  0.905
Plim_1501
PFAM: Heat shock protein 70; KEGG: bca:BCE_1142 DnaK protein, truncation.
 
  0.903
Plim_2333
PFAM: Heat shock protein 70; KEGG: bca:BCE_1142 DnaK protein, truncation.
  
  0.901
Plim_1055
PFAM: glycosyl transferase family 2; Methyltransferase type 12; Methyltransferase type 11; TPR repeat-containing protein; Methionine biosynthesis MetW protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: gbm:Gbem_3740 glycosyl transferase family 2.
   
 0.790
Plim_0664
Hypothetical protein.
       0.773
htpG
Heat shock protein Hsp90; Molecular chaperone. Has ATPase activity.
 
 0.757
Plim_0462
TIGRFAM: polyketide-type polyunsaturated fatty acid synthase PfaA; PFAM: Beta-ketoacyl synthase; KR domain protein; Acyl transferase; short-chain dehydrogenase/reductase SDR; KEGG: gur:Gura_2012 erythronolide synthase.
    
 
 0.750
Your Current Organism:
Planctopirus limnophila
NCBI taxonomy Id: 521674
Other names: P. limnophila DSM 3776, Planctomyces limnophilus ATCC 43296, Planctomyces limnophilus DSM 3776, Planctomyces limnophilus str. DSM 3776, Planctomyces limnophilus strain DSM 3776, Planctopirus limnophila DSM 3776, Planctopirus limnophilus DSM 3776
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