STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
Plim_0909KEGG: afw:Anae109_0040 amino acid-binding ACT domain-containing protein. (153 aa)    
Predicted Functional Partners:
Plim_1303
KEGG: bbr:BB0753 coenzyme A ligase.
 
   0.789
Plim_3882
CapK related-protein; KEGG: proteophosphoglycan ppg4.
 
   0.717
ilvC
Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
     
  0.500
Plim_1722
PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: scl:sce3847 putative serine/threonine dehydratase.
     
  0.500
Plim_0908
PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; nucleic acid binding OB-fold tRNA/helicase-type; type III restriction protein res subunit; SMART: DEAD-like helicase; helicase domain protein; KEGG: ppd:Ppro_2518 ATP-dependent DNA helicase RecG.
       0.482
Plim_0308
Proposed homoserine kinase; KEGG: pca:Pcar_1514 cofactor-independent phosphoglycerate mutase; TIGRFAM: proposed homoserine kinase; phosphonopyruvate decarboxylase-related protein; PFAM: metalloenzyme domain protein.
  
     0.423
Your Current Organism:
Planctopirus limnophila
NCBI taxonomy Id: 521674
Other names: P. limnophila DSM 3776, Planctomyces limnophilus ATCC 43296, Planctomyces limnophilus DSM 3776, Planctomyces limnophilus str. DSM 3776, Planctomyces limnophilus strain DSM 3776, Planctopirus limnophila DSM 3776, Planctopirus limnophilus DSM 3776
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