STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
uvrBExcinuclease ABC, B subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] (707 aa)    
Predicted Functional Partners:
Plim_1595
Excinuclease ABC, A subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.
 
 0.997
Plim_4113
Excinuclease ABC C subunit domain protein; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
 
 
 0.996
Plim_0682
PFAM: ABC transporter related; KEGG: sfu:Sfum_1602 excinuclease ABC, A subunit.
 
 
 0.995
Plim_3242
ABC transporter related protein.
 
 
 0.995
Plim_1235
PFAM: UvrD/REP helicase; KEGG: gme:Gmet_2724 UvrD/REP helicase.
  
 
 0.871
Plim_0849
PFAM: UvrD/REP helicase; KEGG: bsu:BSU06610 ATP-dependent DNA helicase.
  
 
 0.868
Plim_2610
Conserved hypothetical protein.
   
 
 0.811
Plim_3457
UvrD/REP helicase.
   
 
 0.811
Plim_0982
PFAM: Pyrrolo-quinoline quinone; SMART: Pyrrolo-quinoline quinone; KEGG: acr:Acry_1741 pyrrolo-quinoline quinone.
       0.625
Plim_2188
PFAM: Tetratricopeptide TPR_2 repeat protein; TPR repeat-containing protein; SMART: BRCT domain protein; Tetratricopeptide domain protein; KEGG: scl:sce3861 MerR family transcriptional regulator.
  
 
 0.552
Your Current Organism:
Planctopirus limnophila
NCBI taxonomy Id: 521674
Other names: P. limnophila DSM 3776, Planctomyces limnophilus ATCC 43296, Planctomyces limnophilus DSM 3776, Planctomyces limnophilus str. DSM 3776, Planctomyces limnophilus strain DSM 3776, Planctopirus limnophila DSM 3776, Planctopirus limnophilus DSM 3776
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