STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-expression
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[Homology]
Score
Plim_1230PFAM: heat shock protein Hsp20; KEGG: dvl:Dvul_0793 heat shock protein HSP20; Belongs to the small heat shock protein (HSP20) family. (164 aa)    
Predicted Functional Partners:
Plim_1174
PFAM: heat shock protein Hsp20; KEGG: dal:Dalk_3684 heat shock protein HSP20; Belongs to the small heat shock protein (HSP20) family.
  
  
  0.976
Plim_1175
PFAM: heat shock protein Hsp20; KEGG: bbt:BBta_7806 putative small heat-shock protein molecular chaperone; Belongs to the small heat shock protein (HSP20) family.
  
  
  0.976
Plim_0603
PFAM: ATPase AAA-2 domain protein; AAA ATPase central domain protein; UvrB/UvrC protein; Torsin; ATPase associated with various cellular activities AAA_5; Clp domain protein; SMART: AAA ATPase; KEGG: bcy:Bcer98_0076 ATPase; Belongs to the ClpA/ClpB family.
  
 
 0.687
Plim_1058
PFAM: ATPase AAA-2 domain protein; Torsin; SMART: AAA ATPase; KEGG: bba:Bd1288 ATP-dependent Clp protease subunit.
  
 
 0.687
clpB
ATP-dependent chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family.
  
 
 0.687
Plim_0683
TIGRFAM: glutamine synthetase, type I; PFAM: glutamine synthetase catalytic region; glutamine synthetase beta-Grasp; KEGG: afw:Anae109_4400 glutamine synthetase, type I.
    
 
 0.590
grpE
GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...]
  
 
 0.464
Plim_0792
PFAM: FxsA cytoplasmic membrane protein; KEGG: dde:Dde_2422 FxsA protein.
   
    0.437
Plim_1229
KEGG: tgr:Tgr7_1931 ATP-dependent DNA helicase RecQ; TIGRFAM: ATP-dependent DNA helicase RecQ; ATP- dependent DNA helicase, RecQ family; PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; HRDC domain protein; SMART: DEAD-like helicase; helicase domain protein; HRDC domain protein.
     
 0.423
Plim_1779
PFAM: ATP-binding region ATPase domain protein; KEGG: mxa:MXAN_1393 ATPase, histidine kinase-, DNA gyrase B-, and HSP90-like domain protein.
  
 
 0.416
Your Current Organism:
Planctopirus limnophila
NCBI taxonomy Id: 521674
Other names: P. limnophila DSM 3776, Planctomyces limnophilus ATCC 43296, Planctomyces limnophilus DSM 3776, Planctomyces limnophilus str. DSM 3776, Planctomyces limnophilus strain DSM 3776, Planctopirus limnophila DSM 3776, Planctopirus limnophilus DSM 3776
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