STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Plim_1246TIGRFAM: 5-formyltetrahydrofolate cyclo-ligase; PFAM: 5-formyltetrahydrofolate cyclo-ligase; KEGG: gme:Gmet_1179 5-formyltetrahydrofolate cyclo- ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. (212 aa)    
Predicted Functional Partners:
folD
Methylenetetrahydrofolate dehydrogenase (NADP(+)); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.
    
 0.927
purN
Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
  
 
 0.926
Plim_3754
Methylenetetrahydrofolate dehydrogenase (NADP(+)).
     
  0.900
Plim_1245
PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; type III restriction protein res subunit; SMART: DEAD-like helicase; helicase domain protein; KEGG: afw:Anae109_3468 DEAD/DEAH box helicase domain-containing protein.
       0.718
Plim_2311
PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; KEGG: rsh:Rsph17029_3397 nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase.
    
 0.705
thiL
Thiamine-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family.
       0.585
Plim_1385
PFAM: Rhomboid family protein; KEGG: asa:ASA_4287 GlpG protein.
  
  
 0.452
Plim_1588
PFAM: Rhomboid family protein; KEGG: sus:Acid_2217 rhomboid family protein.
  
  
 0.452
Plim_1953
PFAM: Rhomboid family protein; KEGG: dol:Dole_1727 rhomboid family protein.
  
  
 0.452
Plim_3276
Rhomboid family protein.
  
  
 0.452
Your Current Organism:
Planctopirus limnophila
NCBI taxonomy Id: 521674
Other names: P. limnophila DSM 3776, Planctomyces limnophilus ATCC 43296, Planctomyces limnophilus DSM 3776, Planctomyces limnophilus str. DSM 3776, Planctomyces limnophilus strain DSM 3776, Planctopirus limnophila DSM 3776, Planctopirus limnophilus DSM 3776
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