Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
dnaE2DNA polymerase III, alpha subunit; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase. (1026 aa)    
Predicted Functional Partners:
Plim_1326
KEGG: pla:Plav_2530 nucleotidyltransferase/DNA polymerase.
 
  
 0.977
Plim_1327
KEGG: tmz:Tmz1t_2298 hypothetical protein.
 
  
 0.954
Plim_3591
DNA polymerase III, delta subunit.
  
 
 0.838
Plim_0036
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
    
 
 0.829
Plim_2626
Single-strand binding protein.
   
 
 0.828
dnaX
DNA polymerase III, subunits gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
   
 
 0.786
Plim_1351
KEGG: mgm:Mmc1_1869 DNA polymerase III, delta prime subunit.
   
 
 0.786
Plim_1086
Hypothetical protein.
    
 
 0.659
Plim_3046
Hypothetical protein; KEGG: GH22120 gene product from transcript GH22120- RA.
    
 
 0.659
Plim_0305
DNA-directed DNA polymerase; PFAM: UMUC domain protein DNA-repair protein; KEGG: oan:Oant_2282 DNA-directed DNA polymerase.
  
  
 0.529
Your Current Organism:
Planctopirus limnophila
NCBI taxonomy Id: 521674
Other names: P. limnophila DSM 3776, Planctomyces limnophilus ATCC 43296, Planctomyces limnophilus DSM 3776, Planctomyces limnophilus str. DSM 3776, Planctomyces limnophilus strain DSM 3776, Planctopirus limnophila DSM 3776, Planctopirus limnophilus DSM 3776
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