Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Plim_1350PFAM: biotin/lipoyl attachment domain-containing protein; KEGG: eli:ELI_06130 pyruvate dehydrogenase E2 component. (95 aa)    
Predicted Functional Partners:
Plim_0622
TIGRFAM: 2-oxoglutarate dehydrogenase, E1 subunit; PFAM: Transketolase central region; dehydrogenase E1 component; KEGG: scl:sce5670 alpha-ketoglutarate decarboxylase.
  
 0.970
Plim_2074
Hypothetical protein; KEGG: sus:Acid_0979 putative xanthan lyase.
  
 0.866
Plim_2591
Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3)-like protein.
  
 0.866
Plim_3309
KEGG: swi:Swit_0769 short chain dehydrogenase.
  
 0.866
Plim_3567
Pyridine nucleotide-disulfide oxidoreductase dimerization region.
  
 0.866
Plim_3532
2-oxo-acid dehydrogenase E1 subunit, homodimeric type; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
  
 
 0.863
sucC
succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
  
 
 0.827
Plim_0237
PFAM: ATP-binding region ATPase domain protein; GAF domain protein; Forkhead-associated protein; SMART: ATP-binding region ATPase domain protein; GAF domain protein; Forkhead-associated protein; KEGG: scl:sce0793 two-component histidine kinase.
    
 0.767
sucD
succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
  
 
 0.764
Plim_1351
KEGG: mgm:Mmc1_1869 DNA polymerase III, delta prime subunit.
       0.737
Your Current Organism:
Planctopirus limnophila
NCBI taxonomy Id: 521674
Other names: P. limnophila DSM 3776, Planctomyces limnophilus ATCC 43296, Planctomyces limnophilus DSM 3776, Planctomyces limnophilus str. DSM 3776, Planctomyces limnophilus strain DSM 3776, Planctopirus limnophila DSM 3776, Planctopirus limnophilus DSM 3776
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