Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Plim_1373Ribulose-1,5-bisphosphate carboxylase/oxygenase large subunit; PFAM: ribulose bisphosphate carboxylase large chain; Cupin 2 conserved barrel domain protein; KEGG: predicted protein. (551 aa)    
Predicted Functional Partners:
Plim_1253
Carbonic anhydrase/acetyltransferase isoleucine patch superfamily-like protein; KEGG: pen:PSEEN4268 transferase family protein.
   
 
 0.838
Plim_1747
PFAM: class II aldolase/adducin family protein; KEGG: sus:Acid_1334 class II aldolase/adducin family protein.
  
  
 0.800
mtnA
Translation initiation factor, aIF-2BI family; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
 
  
 0.789
Plim_4098
O-acetylhomoserine/O-acetylserine sulfhydrylase; KEGG: proteophosphoglycan 5.
   
 
 0.753
Plim_2467
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
  
 0.743
priA
Primosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily.
  
    0.583
Plim_3996
5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.
   
 
 0.574
nadE
NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
  
  
 0.542
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
     
 0.517
Plim_1664
PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: aba:Acid345_1355 transcriptional regulator, LysR family.
  
  
 0.512
Your Current Organism:
Planctopirus limnophila
NCBI taxonomy Id: 521674
Other names: P. limnophila DSM 3776, Planctomyces limnophilus ATCC 43296, Planctomyces limnophilus DSM 3776, Planctomyces limnophilus str. DSM 3776, Planctomyces limnophilus strain DSM 3776, Planctopirus limnophila DSM 3776, Planctopirus limnophilus DSM 3776
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