STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
Plim_2285Aconitate hydratase 1; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (890 aa)    
Predicted Functional Partners:
Plim_0895
KEGG: bha:BH3160 methylcitrate synthase; TIGRFAM: 2-methylcitrate synthase/citrate synthase II; PFAM: Citrate synthase; Belongs to the citrate synthase family.
 
 0.998
Plim_2962
2-methylcitrate synthase.
 
 0.998
Plim_0079
PFAM: isocitrate/isopropylmalate dehydrogenase; KEGG: mca:MCA3071 isocitrate dehydrogenase, NAD- dependent, putative.
 
 0.973
fumC
Fumarate lyase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
  
 0.951
atpA
ATP synthase F1, alpha subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family.
   
 0.886
Plim_1499
PFAM: Enoyl-CoA hydratase/isomerase; KEGG: mag:amb0852 enoyl-CoA hydratase.
   
 0.884
Plim_2453
TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein; KEGG: scl:sce6555 succinate dehydrogenase/fumarate reductase iron-sulfur subunit.
  
 
 0.883
rpmF
Ribosomal protein L32; Belongs to the bacterial ribosomal protein bL32 family.
   
 0.848
rpsB
Ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family.
   
  0.836
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family.
  
 0.833
Your Current Organism:
Planctopirus limnophila
NCBI taxonomy Id: 521674
Other names: P. limnophila DSM 3776, Planctomyces limnophilus ATCC 43296, Planctomyces limnophilus DSM 3776, Planctomyces limnophilus str. DSM 3776, Planctomyces limnophilus strain DSM 3776, Planctopirus limnophila DSM 3776, Planctopirus limnophilus DSM 3776
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