Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Plim_2387KEGG: bcb:BCB4264_A5103 transcriptional regulator, DeoR family. (250 aa)    
Predicted Functional Partners:
nuoB
NADH-quinone oxidoreductase, B subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
       0.794
Plim_0808
PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: gme:Gmet_2723 alkyl hydroperoxide reductase/thiol specific antioxidant/Mal allergen.
  
    0.739
Plim_0747
PFAM: ferric-uptake regulator; KEGG: scl:sce7206 FUR family regulator protein; Belongs to the Fur family.
  
    0.705
Plim_2145
PFAM: ferric-uptake regulator; KEGG: ank:AnaeK_3863 ferric uptake regulator, Fur family; Belongs to the Fur family.
  
    0.705
Plim_2389
KEGG: bcy:Bcer98_3579 FeS assembly ATPase SufC; TIGRFAM: FeS assembly ATPase SufC; PFAM: ABC transporter related; SMART: AAA ATPase.
  
  
 0.704
Plim_2390
TIGRFAM: FeS assembly protein SufB; PFAM: SufBD protein; KEGG: bcy:Bcer98_3575 FeS assembly protein SufB.
  
  
 0.568
Plim_2391
TIGRFAM: FeS assembly protein SufD; PFAM: SufBD protein; KEGG: bha:BH3470 hypothetical protein.
  
  
 0.490
Plim_2392
PFAM: protein of unknown function DUF59; Rieske [2Fe-2S] domain protein; KEGG: oca:OCAR_4240 NifU protein.
     
 0.457
Plim_3738
Hypothetical protein.
  
     0.450
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
     0.424
Your Current Organism:
Planctopirus limnophila
NCBI taxonomy Id: 521674
Other names: P. limnophila DSM 3776, Planctomyces limnophilus ATCC 43296, Planctomyces limnophilus DSM 3776, Planctomyces limnophilus str. DSM 3776, Planctomyces limnophilus strain DSM 3776, Planctopirus limnophila DSM 3776, Planctopirus limnophilus DSM 3776
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