Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Plim_2585alpha-L-glutamate ligase, RimK family; Belongs to the RimK family. (324 aa)    
Predicted Functional Partners:
mch
Methenyltetrahydromethanopterin cyclohydrolase; Catalyzes the hydrolysis of methenyl-H(4)MPT(+) to 5-formyl- H(4)MPT; Belongs to the MCH family.
 
     0.918
Plim_2407
PFAM: triphosphoribosyl-dephospho-CoA protein; KEGG: lch:Lcho_3148 triphosphoribosyl-dephospho-CoA protein.
     0.814
Plim_1421
PFAM: glutamate synthase alpha subunit domain protein; KEGG: msl:Msil_2403 formylmethanofuran dehydrogenase subunit C.
 
     0.672
Plim_3754
Methylenetetrahydrofolate dehydrogenase (NADP(+)).
 
     0.667
Plim_2022
PFAM: protein of unknown function DUF201; KEGG: lch:Lcho_3151 hypothetical protein.
 
     0.662
Plim_2423
TIGRFAM: beta-ribofuranosylaminobenzene 5'- phosphate synthase family; PFAM: GHMP kinase; KEGG: bxe:Bxe_B2430 beta-ribofuranosylaminobenzene 5'-phosphate synthase.
 
     0.651
Plim_1687
TIGRFAM: formylmethanofuran dehydrogenase subunit A; PFAM: Amidohydrolase 3; KEGG: noc:Noc_0024 DNA/RNA non-specific endonuclease.
 
     0.647
ffsA
Formylmethanofuran/tetrahydromethanopterin N- formyltransferase; Catalyzes the transfer of a formyl group from 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) to methanofuran (MFR) so as to produce formylmethanofuran (formyl-MFR) and tetrahydromethanopterin (H(4)MPT); Belongs to the FTR family.
 
     0.643
Plim_2035
PFAM: dihydropteroate synthase DHPS; KEGG: mca:MCA1245 pterin-binding domain-containing protein.
  
     0.631
rplW
Ribosomal protein L25/L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family.
    
   0.625
Your Current Organism:
Planctopirus limnophila
NCBI taxonomy Id: 521674
Other names: P. limnophila DSM 3776, Planctomyces limnophilus ATCC 43296, Planctomyces limnophilus DSM 3776, Planctomyces limnophilus str. DSM 3776, Planctomyces limnophilus strain DSM 3776, Planctopirus limnophila DSM 3776, Planctopirus limnophilus DSM 3776
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