STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Plim_2822methionine-R-sulfoxide reductase. (150 aa)    
Predicted Functional Partners:
msrA
Peptide methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
 
 0.992
Plim_2038
PFAM: Thioredoxin domain; KEGG: sfu:Sfum_2885 cytochrome c biogenesis protein, transmembrane region.
  
 
 0.680
Plim_0196
KEGG: sus:Acid_5380 hypothetical protein.
    
 
 0.657
Plim_0535
PFAM: cytochrome c biogenesis protein transmembrane region; KEGG: sus:Acid_6757 redoxin domain-containing protein.
    
 
 0.657
Plim_1636
Thiol:disulfide interchange protein-like protein; KEGG: ank:AnaeK_0626 cytochrome c biogenesis protein transmembrane region.
    
 
 0.657
grpE
GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...]
   
 
 0.637
Plim_2820
Hypothetical protein.
       0.636
Plim_2821
Conserved hypothetical protein.
       0.636
Plim_1499
PFAM: Enoyl-CoA hydratase/isomerase; KEGG: mag:amb0852 enoyl-CoA hydratase.
    
 
 0.502
Plim_2823
Hypothetical protein.
       0.488
Your Current Organism:
Planctopirus limnophila
NCBI taxonomy Id: 521674
Other names: P. limnophila DSM 3776, Planctomyces limnophilus ATCC 43296, Planctomyces limnophilus DSM 3776, Planctomyces limnophilus str. DSM 3776, Planctomyces limnophilus strain DSM 3776, Planctopirus limnophila DSM 3776, Planctopirus limnophilus DSM 3776
Server load: low (20%) [HD]