STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Plim_2827D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (546 aa)    
Predicted Functional Partners:
serC
Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
 
 0.985
Plim_1680
PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; KEGG: rec:RHECIAT_CH0002310 putative phosphoglycerate dehydrogenase protein.
  
  
 
0.919
Plim_0649
PFAM: Phosphoglycerate mutase; KEGG: reu:Reut_A0479 phosphoglycerate mutase.
    
  0.903
Plim_0308
Proposed homoserine kinase; KEGG: pca:Pcar_1514 cofactor-independent phosphoglycerate mutase; TIGRFAM: proposed homoserine kinase; phosphonopyruvate decarboxylase-related protein; PFAM: metalloenzyme domain protein.
     
  0.900
Plim_0773
Phosphonopyruvate decarboxylase-related protein; KEGG: sat:SYN_02641 cofactor-independent phosphoglycerate mutase; TIGRFAM: phosphonopyruvate decarboxylase-related protein; PFAM: metalloenzyme domain protein.
     
  0.900
rplF
Ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.
    
   0.776
Plim_2963
Threonine synthase.
 
  
 0.682
rplB
Ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.
    
   0.654
Plim_3500
Histone deacetylase.
    
 0.649
rplQ
TIGRFAM: ribosomal protein L17; PFAM: ribosomal protein L17; KEGG: pla:Plav_2761 ribosomal protein L17.
   
   0.558
Your Current Organism:
Planctopirus limnophila
NCBI taxonomy Id: 521674
Other names: P. limnophila DSM 3776, Planctomyces limnophilus ATCC 43296, Planctomyces limnophilus DSM 3776, Planctomyces limnophilus str. DSM 3776, Planctomyces limnophilus strain DSM 3776, Planctopirus limnophila DSM 3776, Planctopirus limnophilus DSM 3776
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