| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Plim_0611 | Plim_2467 | Plim_0611 | Plim_2467 | Cystathionine gamma-synthase; PFAM: Cys/Met metabolism pyridoxal-phosphate- dependent protein; DegT/DnrJ/EryC1/StrS aminotransferase; KEGG: afw:Anae109_3845 cystathionine gamma-lyase. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.976 |
| Plim_0611 | Plim_2737 | Plim_0611 | Plim_2737 | Cystathionine gamma-synthase; PFAM: Cys/Met metabolism pyridoxal-phosphate- dependent protein; DegT/DnrJ/EryC1/StrS aminotransferase; KEGG: afw:Anae109_3845 cystathionine gamma-lyase. | Pyridoxal-5'-phosphate-dependent protein beta subunit. | 0.964 |
| Plim_0611 | Plim_2758 | Plim_0611 | Plim_2758 | Cystathionine gamma-synthase; PFAM: Cys/Met metabolism pyridoxal-phosphate- dependent protein; DegT/DnrJ/EryC1/StrS aminotransferase; KEGG: afw:Anae109_3845 cystathionine gamma-lyase. | Sulfite reductase (NADPH); Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. | 0.925 |
| Plim_0611 | Plim_2776 | Plim_0611 | Plim_2776 | Cystathionine gamma-synthase; PFAM: Cys/Met metabolism pyridoxal-phosphate- dependent protein; DegT/DnrJ/EryC1/StrS aminotransferase; KEGG: afw:Anae109_3845 cystathionine gamma-lyase. | Cysteine synthase A. | 0.966 |
| Plim_0611 | Plim_3056 | Plim_0611 | Plim_3056 | Cystathionine gamma-synthase; PFAM: Cys/Met metabolism pyridoxal-phosphate- dependent protein; DegT/DnrJ/EryC1/StrS aminotransferase; KEGG: afw:Anae109_3845 cystathionine gamma-lyase. | FAD-binding domain protein. | 0.915 |
| Plim_0611 | Plim_3256 | Plim_0611 | Plim_3256 | Cystathionine gamma-synthase; PFAM: Cys/Met metabolism pyridoxal-phosphate- dependent protein; DegT/DnrJ/EryC1/StrS aminotransferase; KEGG: afw:Anae109_3845 cystathionine gamma-lyase. | Cysteine synthase A; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.966 |
| Plim_0611 | Plim_3306 | Plim_0611 | Plim_3306 | Cystathionine gamma-synthase; PFAM: Cys/Met metabolism pyridoxal-phosphate- dependent protein; DegT/DnrJ/EryC1/StrS aminotransferase; KEGG: afw:Anae109_3845 cystathionine gamma-lyase. | Cystathionine gamma-lyase. | 0.916 |
| Plim_0611 | Plim_4098 | Plim_0611 | Plim_4098 | Cystathionine gamma-synthase; PFAM: Cys/Met metabolism pyridoxal-phosphate- dependent protein; DegT/DnrJ/EryC1/StrS aminotransferase; KEGG: afw:Anae109_3845 cystathionine gamma-lyase. | O-acetylhomoserine/O-acetylserine sulfhydrylase; KEGG: proteophosphoglycan 5. | 0.933 |
| Plim_0611 | ahcY | Plim_0611 | Plim_3615 | Cystathionine gamma-synthase; PFAM: Cys/Met metabolism pyridoxal-phosphate- dependent protein; DegT/DnrJ/EryC1/StrS aminotransferase; KEGG: afw:Anae109_3845 cystathionine gamma-lyase. | Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | 0.919 |
| Plim_0611 | metXA | Plim_0611 | Plim_1427 | Cystathionine gamma-synthase; PFAM: Cys/Met metabolism pyridoxal-phosphate- dependent protein; DegT/DnrJ/EryC1/StrS aminotransferase; KEGG: afw:Anae109_3845 cystathionine gamma-lyase. | Homoserine O-acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. | 0.922 |
| Plim_2467 | Plim_0611 | Plim_2467 | Plim_0611 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Cystathionine gamma-synthase; PFAM: Cys/Met metabolism pyridoxal-phosphate- dependent protein; DegT/DnrJ/EryC1/StrS aminotransferase; KEGG: afw:Anae109_3845 cystathionine gamma-lyase. | 0.976 |
| Plim_2467 | Plim_2737 | Plim_2467 | Plim_2737 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Pyridoxal-5'-phosphate-dependent protein beta subunit. | 0.885 |
| Plim_2467 | Plim_2758 | Plim_2467 | Plim_2758 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Sulfite reductase (NADPH); Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. | 0.430 |
| Plim_2467 | Plim_2776 | Plim_2467 | Plim_2776 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Cysteine synthase A. | 0.885 |
| Plim_2467 | Plim_3056 | Plim_2467 | Plim_3056 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | FAD-binding domain protein. | 0.796 |
| Plim_2467 | Plim_3256 | Plim_2467 | Plim_3256 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Cysteine synthase A; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.885 |
| Plim_2467 | Plim_3306 | Plim_2467 | Plim_3306 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Cystathionine gamma-lyase. | 0.976 |
| Plim_2467 | Plim_4098 | Plim_2467 | Plim_4098 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | O-acetylhomoserine/O-acetylserine sulfhydrylase; KEGG: proteophosphoglycan 5. | 0.952 |
| Plim_2467 | ahcY | Plim_2467 | Plim_3615 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | 0.951 |
| Plim_2467 | metXA | Plim_2467 | Plim_1427 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Homoserine O-acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. | 0.757 |