STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
yacGProtein of unknown function DUF329; Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C- terminal domain of GyrB, which probably disrupts DNA binding by the gyrase. (75 aa)    
Predicted Functional Partners:
Plim_0106
KEGG: scl:sce4451 DNA gyrase subunit A; PFAM: DNA gyrase/topoisomerase IV subunit A; DNA gyrase repeat beta-propeller; SMART: DNA gyrase/topoisomerase IV subunit A.
    
 
 0.672
Plim_2267
KEGG: mxa:MXAN_0766 DNA gyrase, A subunit; TIGRFAM: DNA gyrase, A subunit; PFAM: DNA gyrase/topoisomerase IV subunit A; DNA gyrase repeat beta-propeller; SMART: DNA gyrase/topoisomerase IV subunit A.
    
 
 0.672
Plim_3385
Protein of unknown function UPF0027.
       0.458
Plim_0105
KEGG: mxa:MXAN_2483 type II DNA topoisomerase, B subunit; PFAM: DNA topoisomerase type IIA subunit B region 2 domain protein; ATP-binding region ATPase domain protein; DNA gyrase subunit B domain protein; SMART: DNA topoisomerase II; ATP-binding region ATPase domain protein.
    
 
 0.454
Plim_0450
PFAM: DNA topoisomerase type IIA subunit B region 2 domain protein; DNA gyrase subunit B domain protein; TOPRIM domain protein; ATP-binding region ATPase domain protein; SMART: DNA topoisomerase II; ATP-binding region ATPase domain protein; KEGG: ank:AnaeK_0004 DNA gyrase, B subunit.
    
 
 0.454
Plim_3565
ATP-binding region ATPase domain protein.
    
 
 0.454
Plim_3383
Lipoate-protein ligase B-like protein; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
       0.419
Your Current Organism:
Planctopirus limnophila
NCBI taxonomy Id: 521674
Other names: P. limnophila DSM 3776, Planctomyces limnophilus ATCC 43296, Planctomyces limnophilus DSM 3776, Planctomyces limnophilus str. DSM 3776, Planctomyces limnophilus strain DSM 3776, Planctopirus limnophila DSM 3776, Planctopirus limnophilus DSM 3776
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