STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Plim_3597AMP-dependent synthetase and ligase. (564 aa)    
Predicted Functional Partners:
Plim_0462
TIGRFAM: polyketide-type polyunsaturated fatty acid synthase PfaA; PFAM: Beta-ketoacyl synthase; KR domain protein; Acyl transferase; short-chain dehydrogenase/reductase SDR; KEGG: gur:Gura_2012 erythronolide synthase.
 
 0.989
Plim_1672
6-deoxyerythronolide-B synthase., (Acyl-carrier- protein) S-malonyltransferase; PFAM: Beta-ketoacyl synthase; peptidase C45 acyl- coenzyme A:6-aminopenicillanic acid acyl-transferase; Acyl transferase; KR domain protein; short-chain dehydrogenase/reductase SDR; KEGG: acp:A2cp1_4042 beta-ketoacyl synthase.
 
 0.987
Plim_2638
Alpha/beta hydrolase fold protein.
 
 0.980
Plim_3324
Beta-ketoacyl synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
 
 0.927
Plim_1635
PFAM: 3-beta hydroxysteroid dehydrogenase/isomerase; Male sterility domain; polysaccharide biosynthesis protein CapD; short-chain dehydrogenase/reductase SDR; NAD-dependent epimerase/dehydratase; KEGG: gbm:Gbem_2099 3-beta hydroxysteroid dehydrogenase/isomerase.
 
 
 0.851
Plim_3323
3-Oxoacyl-(acyl-carrier-protein (ACP)) synthase III domain protein.
   
 0.841
rplF
Ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.
    
  0.833
Plim_3497
Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
   
 
 0.765
rplC
Ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.
   
 
 0.764
rplO
Ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.
    
   0.756
Your Current Organism:
Planctopirus limnophila
NCBI taxonomy Id: 521674
Other names: P. limnophila DSM 3776, Planctomyces limnophilus ATCC 43296, Planctomyces limnophilus DSM 3776, Planctomyces limnophilus str. DSM 3776, Planctomyces limnophilus strain DSM 3776, Planctopirus limnophila DSM 3776, Planctopirus limnophilus DSM 3776
Server load: low (22%) [HD]