Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Plim_3718ParB domain protein nuclease. (223 aa)    
Predicted Functional Partners:
Plim_0187
ATPase; KEGG: rpi:Rpic_0439 ATPase.
  
 
 0.789
Plim_1365
PFAM: Cobyrinic acid ac-diamide synthase; KEGG: bba:Bd3906 partition protein, ParA-like protein.
  
 
 0.789
Plim_3612
Phage terminase-like protein protein large subunit-like protein.
 
     0.769
Plim_3719
Protein of unknown function DUF1549.
       0.746
Plim_3545
Portal protein lambda.
 
     0.689
Plim_3717
Hypothetical protein.
       0.538
Plim_3720
Protein of unknown function DUF1501.
       0.461
Plim_3609
AAA ATPase.
 
     0.458
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
 
  
 0.455
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
     
 0.405
Your Current Organism:
Planctopirus limnophila
NCBI taxonomy Id: 521674
Other names: P. limnophila DSM 3776, Planctomyces limnophilus ATCC 43296, Planctomyces limnophilus DSM 3776, Planctomyces limnophilus str. DSM 3776, Planctomyces limnophilus strain DSM 3776, Planctopirus limnophila DSM 3776, Planctopirus limnophilus DSM 3776
Server load: medium (44%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.