node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
M231_00134 | M231_00148 | A0A4Q1BWP9 | A0A4Q1BWP5 | Acetyl-CoA C-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. | Hydroxymethylglutaryl-CoA lyase. | 0.952 |
M231_00134 | M231_04450 | A0A4Q1BWP9 | A0A4V1M3W4 | Acetyl-CoA C-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. | Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. | 0.974 |
M231_00134 | M231_04634 | A0A4Q1BWP9 | A0A4Q1BK46 | Acetyl-CoA C-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. | 3-hydroxybutyryl-CoA dehydrogenase. | 0.985 |
M231_00134 | M231_06202 | A0A4Q1BWP9 | A0A4Q1BGG8 | Acetyl-CoA C-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. | 3-hydroxyacyl-CoA dehydrogenase. | 0.984 |
M231_00134 | M231_06760 | A0A4Q1BWP9 | A0A4Q1BG19 | Acetyl-CoA C-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | 0.997 |
M231_00134 | M231_07751 | A0A4Q1BWP9 | A0A4Q1BAH2 | Acetyl-CoA C-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. | Uncharacterized protein. | 0.900 |
M231_00148 | M231_00134 | A0A4Q1BWP5 | A0A4Q1BWP9 | Hydroxymethylglutaryl-CoA lyase. | Acetyl-CoA C-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. | 0.952 |
M231_00148 | M231_04450 | A0A4Q1BWP5 | A0A4V1M3W4 | Hydroxymethylglutaryl-CoA lyase. | Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. | 0.963 |
M231_00148 | M231_04634 | A0A4Q1BWP5 | A0A4Q1BK46 | Hydroxymethylglutaryl-CoA lyase. | 3-hydroxybutyryl-CoA dehydrogenase. | 0.462 |
M231_00148 | M231_06202 | A0A4Q1BWP5 | A0A4Q1BGG8 | Hydroxymethylglutaryl-CoA lyase. | 3-hydroxyacyl-CoA dehydrogenase. | 0.462 |
M231_00148 | M231_06760 | A0A4Q1BWP5 | A0A4Q1BG19 | Hydroxymethylglutaryl-CoA lyase. | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | 0.981 |
M231_00148 | M231_07751 | A0A4Q1BWP5 | A0A4Q1BAH2 | Hydroxymethylglutaryl-CoA lyase. | Uncharacterized protein. | 0.900 |
M231_04450 | M231_00134 | A0A4V1M3W4 | A0A4Q1BWP9 | Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. | Acetyl-CoA C-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. | 0.974 |
M231_04450 | M231_00148 | A0A4V1M3W4 | A0A4Q1BWP5 | Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. | Hydroxymethylglutaryl-CoA lyase. | 0.963 |
M231_04450 | M231_04634 | A0A4V1M3W4 | A0A4Q1BK46 | Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. | 3-hydroxybutyryl-CoA dehydrogenase. | 0.938 |
M231_04450 | M231_06202 | A0A4V1M3W4 | A0A4Q1BGG8 | Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. | 3-hydroxyacyl-CoA dehydrogenase. | 0.938 |
M231_04450 | M231_06760 | A0A4V1M3W4 | A0A4Q1BG19 | Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | 0.946 |
M231_04450 | M231_07751 | A0A4V1M3W4 | A0A4Q1BAH2 | Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. | Uncharacterized protein. | 0.900 |
M231_04634 | M231_00134 | A0A4Q1BK46 | A0A4Q1BWP9 | 3-hydroxybutyryl-CoA dehydrogenase. | Acetyl-CoA C-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. | 0.985 |
M231_04634 | M231_00148 | A0A4Q1BK46 | A0A4Q1BWP5 | 3-hydroxybutyryl-CoA dehydrogenase. | Hydroxymethylglutaryl-CoA lyase. | 0.462 |