node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
M231_00270 | M231_03314 | A0A4Q1BVW9 | A0A4Q1BNP8 | Spermidine synthase; Belongs to the spermidine/spermine synthase family. | Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. | 0.402 |
M231_00270 | M231_04019 | A0A4Q1BVW9 | A0A4Q1BLN7 | Spermidine synthase; Belongs to the spermidine/spermine synthase family. | Homoaconitase, mitochondrial; Catalyzes the reversible hydration of cis-homoaconitate to (2R,3S)-homoisocitrate, a step in the alpha-aminoadipate pathway for lysine biosynthesis. | 0.718 |
M231_00270 | M231_05943 | A0A4Q1BVW9 | A0A4Q1BGT8 | Spermidine synthase; Belongs to the spermidine/spermine synthase family. | Homoisocitrate dehydrogenase. | 0.803 |
M231_00276 | M231_01961 | A0A4Q1BW56 | A0A4Q1BRX0 | Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | Isocitrate lyase. | 0.484 |
M231_00276 | M231_03314 | A0A4Q1BW56 | A0A4Q1BNP8 | Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. | 0.740 |
M231_00276 | M231_03462 | A0A4Q1BW56 | A0A4Q1BNF2 | Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | Uncharacterized protein. | 0.795 |
M231_00276 | M231_03509 | A0A4Q1BW56 | A0A4Q1BN83 | Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | Isocitrate dehydrogenase, NAD-dependent. | 0.737 |
M231_00276 | M231_04019 | A0A4Q1BW56 | A0A4Q1BLN7 | Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | Homoaconitase, mitochondrial; Catalyzes the reversible hydration of cis-homoaconitate to (2R,3S)-homoisocitrate, a step in the alpha-aminoadipate pathway for lysine biosynthesis. | 0.740 |
M231_00276 | M231_04267 | A0A4Q1BW56 | A0A4Q1BL36 | Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. | 0.916 |
M231_00276 | M231_04273 | A0A4Q1BW56 | A0A4V1M3Y7 | Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | Citrate synthase; Belongs to the citrate synthase family. | 0.800 |
M231_00276 | M231_04976 | A0A4Q1BW56 | A0A4V1M3Q9 | Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. | 0.473 |
M231_00276 | M231_05943 | A0A4Q1BW56 | A0A4Q1BGT8 | Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | Homoisocitrate dehydrogenase. | 0.531 |
M231_01961 | M231_00276 | A0A4Q1BRX0 | A0A4Q1BW56 | Isocitrate lyase. | Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.484 |
M231_01961 | M231_03314 | A0A4Q1BRX0 | A0A4Q1BNP8 | Isocitrate lyase. | Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. | 0.845 |
M231_01961 | M231_03462 | A0A4Q1BRX0 | A0A4Q1BNF2 | Isocitrate lyase. | Uncharacterized protein. | 0.885 |
M231_01961 | M231_03509 | A0A4Q1BRX0 | A0A4Q1BN83 | Isocitrate lyase. | Isocitrate dehydrogenase, NAD-dependent. | 0.504 |
M231_01961 | M231_04019 | A0A4Q1BRX0 | A0A4Q1BLN7 | Isocitrate lyase. | Homoaconitase, mitochondrial; Catalyzes the reversible hydration of cis-homoaconitate to (2R,3S)-homoisocitrate, a step in the alpha-aminoadipate pathway for lysine biosynthesis. | 0.731 |
M231_01961 | M231_04267 | A0A4Q1BRX0 | A0A4Q1BL36 | Isocitrate lyase. | Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. | 0.689 |
M231_01961 | M231_04273 | A0A4Q1BRX0 | A0A4V1M3Y7 | Isocitrate lyase. | Citrate synthase; Belongs to the citrate synthase family. | 0.920 |
M231_03314 | M231_00270 | A0A4Q1BNP8 | A0A4Q1BVW9 | Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. | Spermidine synthase; Belongs to the spermidine/spermine synthase family. | 0.402 |